Results 51 to 60 of about 1,203,386 (264)
A New Middle Class on Old Academic Grounds: Law Students of the Cluj University in the 1930s
Studia Universitatis Babes-Bolyai Sociologia, 2015 One of the main tasks of universities of Central and Eastern Europe is that of forming loyal and reliable citizens ready to fill in the ranks of public service.
Pálffy Zoltán
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The "Decolonial Turn": What Does It Mean for Academic Staff Development?
Education as Change, 2017 It has become increasingly evident that the discourse of transformation that has shaped the democratising of higher education institutions over the first two decades of the democratic dispensation in South Africa has now run its course. Over the past few
Jo-Anne Vorster, Lynn Quinn
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Collaborative Learning in Higher Education
Open Journal of Social Sciences, 2014 This paper presents the procedures and the outcomes of collaborative activities and of peer tutoring carried out by the students in the teaching of “General Didactics”, held at the University of Roma Tre, in ay 2012/13.
LA ROCCA, CONCETTA +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Nanotechnology Reviews, 2019 BCZT (Ba0.85Ca0.15Zr0.1Ti0.9O3) is a recent class of lead-free ferroelectric material associated with high piezoelectric coefficient, making it suitable to inspire hydroxyapatite (HA)-BCZT ceramics for bone materials. Nano-crystalline hydroxyapatite (HA)
Manohar Chelli Sai +6 more
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