Results 61 to 70 of about 19,827,130 (305)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2020 Type-two constructions abound in cryptography: adversaries for encryption and authentication schemes, if active, are modeled as algorithms having access to oracles, i.e. as second-order algorithms. But how about making cryptographic schemes themselves higher-order?
Barak B., Crubille R., Dal Lago U.
openaire +5 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Polymorphic Higher-order Termination [PDF]
CoRR, 2019 author copy of a paper accepted for FSCD 2019, with an extended ...
Lukasz Czajka 0001, Cynthia Kop
openaire +5 more sources
A Seventh-Order Scheme for Computing the Generalized Drazin Inverse
Mathematics, 2019 One of the most important generalized inverses is the Drazin inverse, which is defined for square matrices having an index. The objective of this work is to investigate and present a computational tool in the form of an iterative method for computing ...
Dilan Ahmed +3 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Vibration and buckling analysis of functionally graded sandwich beams by a new higher-order shear deformation theory [PDF]
, 2015 This paper proposes a new higher-order shear deformation theory for buckling and free vibration analysis of isotropic and functionally graded (FG) sandwich beams.
Thai, Huu-Tai +3 more
core +1 more source
Applied Mathematics in Science and EngineeringIn this paper, we introduce the probabilistic Bernoulli numbers, Cauchy numbers, and Euler numbers of order α associated with the random variable Y, utilizing the generating function approach.
Aimin Xu
doaj +1 more source
A Fast Derivative-Free Iteration Scheme for Nonlinear Systems and Integral Equations
Mathematics, 2019 Derivative-free schemes are a class of competitive methods since they are one remedy in cases at which the computation of the Jacobian or higher order derivatives of multi-dimensional functions is difficult.
Mozafar Rostami +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source