Results 81 to 90 of about 19,827,130 (305)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

C1,α-rectifiability in low codimension in Heisenberg groups

Analysis and Geometry in Metric Spaces
A natural higher-order notion of C1,α{C}^{1,\alpha }-rectifiability ...
Idu Kennedy Obinna, Maiale Francesco Paolo   +1 more
doaj   +1 more source

Rebranding exercise: closing the gap between values and behavior

International Journal of Behavioral Nutrition and Physical Activity, 2011
Background Behavior can only be understood by identifying the goals to which it is attached. Superordinate-level goals are linked to individuals' values, and may offer insights into how to connect exercise with their core values and increase ...
Eccles Jacquelynne S, Segar Michelle L, Richardson Caroline R   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Application of Power Spectrum, Cepstrum, Higher Order Spectrum and Neural Network Analyses for Induction Motor Fault Diagnosis [PDF]

, 2013
The power spectrum is defined as the square of the magnitude of the Fourier transform (FT) of a signal. The advantage of FT analysis is that it allows the decomposition of a signal into individual periodic frequency components and establishes the ...
Liang, B., Liang, Bo, Iwnicki, S. D., Zhao, Y., Iwnicki, S.   +4 more
core   +1 more source

New Generalized Algorithm for Developing k-Step Higher Derivative Block Methods for Solving Higher Order Ordinary Differential Equations

Journal of Mathematical and Fundamental Sciences, 2018
his article presents a new generalized algorithm for developing k-step (m+1)^th derivative block methods for solving m^th order ordinary differential equations.
Oluwaseun Adeyeye , Zurni Omar
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Higher order sigma point filter: A new heuristic for nonlinear time series filtering [PDF]

, 2013
In this paper we present some new results related to the higher order sigma point filter (HOSPoF), introduced in [1] for filtering nonlinear multivariate time series. This paper makes two distinct contributions.
Date, P, Ponomareva, K
core   +1 more source

Forced oscillation for higher order functional differential equations

Electronic Journal of Differential Equations, 2012
We establish some oscillation criteria for the solutions to forced higher-order differential equations. We do not assume that the forcing term is the n-th derivative of an oscillatory function, and do not assume that the coefficients are of a definite
Yuan Gong Sun, Taher S. Hassan
doaj