Results 91 to 100 of about 19,827,130 (305)

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Higher-Order Intentionality and Higher-Order Acquaintance [PDF]

open access: yesPhilosophical Studies, 2006
I argue against such “Higher-Order Intentionalist” theories of consciousness as the higher-order thought and inner sense views on the ground that they understand a subject’s awareness of his or her phenomenal characters to be intentional, like seeming-seeing, rather than “direct”, like seeing.
openaire   +1 more source

Design LQR Controller for Higher Order Systems Based on the Reduction Model

open access: yesJournal of Engineering and Sustainable Development, 2015
This paper present a simple method for reducing the linear higher order systems. The coefficient of the reduction model is obtained by using the modified dominant pole technique, while the coefficients of the numerator are obtained by reduced order ...
Noor Safaa Abdul-Jaleel
doaj  

A positive image as an object of social perception of the commanders of the Traffic Police Road Patrol Service

open access: yesПсихология и право
Context and relevance. Modern realities and the severity of personnel problems in the internal affairs bodies place high demands on police officers who promote social norms.
S.E. Borisova
doaj   +1 more source

Pedagogical conservatism of university teachers [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Акмеология образования. Психология развития
The relevance of the research is due to the need to implement the principle of cooperation and interaction of the subjects of the educational process, and to use the creative approach in the situation of modernizing higher education.
Avakyan, Inna B.
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Development of Higher Order Stiffened Shell Element (HOST9) for the Static Analysis of Stiffened Laminated Plates

open access: yesCivil and Environmental Engineering
A new higher order stiffened shell element (HOST9) is developed comprising of a 9 noded flat shell element and a 3 noded stiffener element for analysis of stiffened laminated plates. The shell element is a lagrangian element.
Sheth Karan, Joshi Rajendra
doaj   +1 more source

Forced-Perturbed Fractional Differential Equations of Higher Order: Asymptotic Properties of Non-Oscillatory Solutions

open access: yesFractal and Fractional
This study investigates the asymptotic behavior of non-oscillatory solutions to forced-perturbed fractional differential equations with the Caputo fractional derivative.
Said R. Grace   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The looming financial crisis facing Connecticut public higher education.

open access: yes, 1997
Title from cover.; "December 1997."; Erratum sheet inserted.; Harvested from the web on 10/16 ...
Connecticut. Dept. of Higher Education.
core  

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