Results 111 to 120 of about 4,523,229 (316)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
A Higher-Order Iterative Path Ordering [PDF]
, 2008 The higher-order recursive path ordering ( HORPO ) defined by Jouannaud and Rubio provides a method to prove termination of higher-order rewriting. We present an iterative version of HORPO by means of an auxiliary term rewriting system, following an approach originally due to Bergstra and Klop.
Cynthia Kop, Femke van Raamsdonk
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Genetic algorithm optimization for blind channel identification with higher order cumulant fitting
, 1997 —An important family of blind equalization algorithms identify a communication channel model based on fitting higher order cumulants, which poses a nonlinear optimization prob-lem.
Y. Wu +5 more
core
Superpixel Optimization Using Higher Order Energy
, 2016 A novel superpixel extraction algorithm using a higher order energy optimization framework is proposed in this paper. We first adopt the k-means clustering technique to quickly get an initial superpixel result.
Li, Xuelong +3 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
IEEE Transactions on Information Theory, 2014 We introduce {\bf complementary information set codes} of higher-order. A binary linear code of length $tk$ and dimension $k$ is called a complementary information set code of order $t$ ($t$-CIS code for short) if it has $t$ pairwise disjoint information sets. The duals of such codes permit to reduce the cost of masking cryptographic algorithms against
Claude Carlet +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Validating and Animating Higher-Order Recursive Functions in B
, 2007 ProB is an animation and model checking tool for the B Method, which can deal with many interesting specifications. Some specifications, however, contain complicated functions which cannot be represented explicitly by a tool.
Leuschel, Michael +2 more
core
Existence of periodic solutions for higher-order nonlinear difference equations
Electronic Journal of Differential Equations, 2016 In this article, we study a higher-order nonlinear difference equation. By using critical point theory, we establish sufficient conditions for the existence of periodic solutions.
Jianhua Leng
doaj