Results 51 to 60 of about 99,655 (264)

Scientific Artificial Intelligence: From a Procedural Toolkit to Cognitive Coauthorship

Philosophies
This article proposes a redefinition of scientific authorship under conditions of algorithmic mediation. We shift the discussion from the ontological dichotomy of “tool versus author” to an operationalizable epistemology of contribution.
Adilbek K. Bisenbaev
doaj   +1 more source

Inter-budget Relations in Kazakhstan: State and Main Trends [PDF]

Финансовый журнал
Balance of the state budget is one of the necessary conditions for the effective functioning of the budget system of the country. This balance is largely determined by inter-governmental fiscal relations and the resulting redistribution of financial ...
Vyacheslav Yu. Dodonov
doaj   +1 more source

An Analysis of the Relevance between the State Islamic Religious Higher Education Institutions (Perguruan Tinggi Keagamaan Islam Negeri) and the Ministry of Religious Affairs Strategic Plans in Developing Higher Education Quality

Al-Tadzkiyyah: Jurnal Pendidikan Islam, 2023
The strategic plan of the Ministry of Religious Affairs of the Republic of Indonesia must be elaborated hierarchically into the strategic plans of Islamic Religious Higher Education Institutions based on their respective potential.
Deden Makbulloh, Iin Yulianti
doaj   +1 more source

Cysteine Redox State Governs the Condensation Pathway of Hendra Virus W Protein and Differentially Impacts Type I IFN and NF‐κB Signaling

Advanced Science, EarlyView.
The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud, Alexandre Lalande, Giulia Pesce, Auriane Bouchet, Carole Meunier, Christophe Bignon, Denis Ptchelkine, Yu Gu, Eva Ogire, Pierre‐Yves Lozach, Denis Gerlier, Cyrille Mathieu, Sonia Longhi   +12 more
wiley   +1 more source

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

Public Higher Education Studies: Developing a Multicultural-Based Islamic Religious Education Learning Model

Tadris: Jurnal Keguruan dan Ilmu Tarbiyah, 2020
The purpose of this study was to develop a multicultural-based Islamic religious education learning model to develop students’ religious tolerance in Lampung and Banten Provinces. This study employed the research and development design. The research data
Imam Syafei, Wasehudin Wasehudin, Guntur Cahaya Kesuma, Septuri Septuri, Ade Imelda Frimayanti   +4 more
doaj   +1 more source

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Advanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen, Haoyu You, Hefa Huang, Huihui Chai, Ruize Zhu, Yun Guan, Qisheng Tang, Tianwen Li, Shan Jiang, Houshi Xu, Peng Wang, Yue Wang, Maoyuan Sun, Beining Liu, Zhen Li, Yulai Zeng, Weiqiu Ping, Yanlin Teng, Songlin Yan, Qinghui Li, Long Gu, Tao Sun, Zhifeng Shi   +22 more
wiley   +1 more source

Religious policy of Kazakhstan: mechanisms for managing the Islamic environment amid post-soviet transformation

Frontiers in Political Science
This research investigates the transformation of Kazakhstan's religious landscape following independence from the Soviet Union, with particular emphasis on state regulatory mechanisms governing Islamic practices.
Sholpan Zhandossova, Natalya Seitakhmetova, Marhabbat Nurov   +2 more
doaj   +1 more source

Charting the Future of Stereoselective Carbohydrate Synthesis: The Essential Role of Cross‐Disciplinary Innovation

Advanced Science, EarlyView.
Cross‐disciplinary endeavors are blossoming across the broad chemical sciences. This perspective provides a glimpse into the rewarding interdisciplinary journey taken by the Charles Loh research group in pioneering the σ‐hole based catalytic glycosylation strategy.
Charles C. J. Loh
wiley   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source