Results 121 to 130 of about 13,575,187 (324)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Diarrea recurrente por Cystoisopora belli en pacientes con infección por VIH con TARGA

Revista Peruana de Medicina Experimental y Salud Pública
La Cystoisospora belli, antes denominada Isospora belli, es el agente etiológico de la cystoisosporiasis, una infección oportunista que afecta a pacientes inmunodeprimidos, caracterizada por diarrea crónica y pérdida ponderal.
Raúl Montalvo, Eduardo Ticona, Marcos Ñavincopa, Yuri García, Gonzalo Chávez, Víctor Chávez, Jorge Arévalo, Jaime Soria, Alina Huiza   +8 more
doaj   +2 more sources

Lamivudine’s hypersensitivity in an HIV infected patient: case report

Medicina, 2017
Relevance: To report a case of hypersensitivity to lamivudine, a medicine that is considered safe and is indicated as part of the initial therapy for HIV infected patients.
Vitor R. G. A. Valviesse, Leonardo I. de Pinho, Rodrigo F. Freitas, Andrea G. Varon, Alberto S. Lemos   +4 more
doaj   +1 more source

Cu-CHA material efficient in the SCR process in the presence of water and CO2 [PDF]

, 2017
A reproducible method for the synthesis of SCR active Cu-CHA materials has been developed, which allows the incorporation of up to 4% of copper inside the cavities of the zeolite.
Alemany-Arrebola, Luis Jose, Cortés Reyes, Marina, Herrera-Delgado, Maria Concepcion, Larrubia-Vargas, María Ángeles   +3 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Rosuvastatina e ciprofibrato no tratamento da dislipidemia em pacientes com HIV Rosuvastatin and ciprofibrate in the treatment of dyslipidemia in patients with HIV

Arquivos Brasileiros de Cardiologia, 2012
FUNDAMENTO: A dislipidemia secundária à terapia antirretroviral potente nos pacientes com HIV está associada à significativa elevação da morbimortalidade cardiovascular por doença aterosclerótica, sendo, portanto, necessário tratamento imediato e eficaz.
Hamilton Domingos, Rivaldo Venâncio da Cunha, Anamaria Mello Miranda Paniago, Albert Schiaveto de Souza, Renata London Rodrigues, João Américo Domingos   +5 more
doaj  

Recent Advance in Heterocyclic Organozinc and Organomanganese Compounds; Direct Synthetic Routes and Application in Organic Synthesis

Molecules, 2010
A practical synthetic route for the preparation of 2-pyridyl and 3-pyridyl derivatives has been accomplished by utilizing a simple coupling reaction of stable 2-pyridylzinc bromides and 3-pyridylzinc bromides.
Reuben D. Rieke, Seung-Hoi Kim
doaj   +1 more source

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

eLife, 2016
We recently found that nucleosomes directly block access of CRISPR/Cas9 to DNA (Horlbeck et al., 2016). Here, we build on this observation with a comprehensive algorithm that incorporates chromatin, position, and sequence features to accurately predict ...
Max A. Horlbeck, Luke A. Gilbert, Jacqueline E. Villalta, Britt Adamson, Ryan A. Pak, Yuwen Chen, Alexander P. Fields, C. Park, J. Corn, M. Kampmann, J. Weissman   +10 more
semanticscholar   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Avalanche Dynamics for Active Matter in Heterogeneous Media

, 2017
Using numerical simulations, we examine the dynamics of active matter run-and-tumble disks moving in a disordered array of obstacles. As a function of increasing active disk density and activity, we find a transition from a completely clogged state to a ...
Reichhardt, C., Reichhardt, C. J. O.
core   +1 more source