Results 101 to 110 of about 8,362,360 (307)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Blacks about to attack Leichardt's Camp, near the Gulf of Carpentaria, 1845 [picture] /

open access: yes, 1890
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an9025855-4; Exhibited: "Mr. Gilbert's Beautiful Parrakeet", National Library of Australia Visitor Centre, 22 June - 14 October 2007 ...
Macfarlane, J., active 1890-1898.
core  

Symmetry breaking of highly symmetrical nanoclusters for triggering highly optical activity

open access: yesFundamental Research
Developing new approaches to fulfill the enantioseparation of nanocluster racemates and construct cluster-based nanomaterials with optical activity remains highly desired in cluster science, because it is an essential prerequisite for fundamental research and extensive applications of these nanomaterials.
Xiao Wei   +6 more
openaire   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Sturt's party threatened by blacks at the junction of the Murray and Darling, 1830 [picture] /

open access: yes, 1890
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an9025855 ...
Macfarlane, J., active 1890-1898.
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Adherence to and effectiveness of Highly Active Antiretroviral Treatment for HIV infection: assessing the bidirectional relationship [PDF]

open access: yes
It is well-established that high adherence to HAART is a major determinant of virological and immunological success. Furthermore, psycho-social research has identified a wide range of adherence factors.
François Raffi   +9 more
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Captain Rossiter comes to Eyre's aid, Great Australian Bight, 1841 [picture] /

open access: yes, 1890
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an9025855 ...
Macfarlane, J., active 1890-1898.
core  

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