Results 91 to 100 of about 8,362,360 (307)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Journal of Family Medicine and Primary CareBackground: India has demonstrated an overall reduction of 57% in estimated annual new HIV infections. Assessing the quality of the ART Centers (ARTC) services would enable us to focus on the gaps and take necessary measures to provide high-quality ART ...
G. Jahnavi +4 more
doaj +1 more source
Disseminated kaposi's sarcoma in an HIV-positive patient: A rare entity in an Indian patient
Indian Journal of Dermatology, 2016 AIDS-associated disseminated Kaposi sarcoma (KS) is a rare entity, especially in India due to the low prevalence of human herpes virus-8 infections in Indian population.
Biswanath Behera +4 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Dentistry JournalPeriodontal disease (PD) is an inflammatory condition caused by multiple periodontal pathogens, particularly those belonging to the Red Complex. Various risk factors influence the development of PD, including age, sex, socioeconomic status, ethnicity ...
Bhavyasri Gaddam +13 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
, 1890 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an9025855-6; Exhibited: Scottish Australia, Art Gallery of Ballarat, Mid July - late July ...
Macfarlane, J., active 1890-1898.
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
John McDouall Stuart planting the Union Jack on Central Mount Stuart, 1860 [picture] /
, 1890 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an9025855 ...
Macfarlane, J., active 1890-1898.
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