Results 81 to 90 of about 8,362,360 (307)

Recent Advance in Heterocyclic Organozinc and Organomanganese Compounds; Direct Synthetic Routes and Application in Organic Synthesis

open access: yesMolecules, 2010
A practical synthetic route for the preparation of 2-pyridyl and 3-pyridyl derivatives has been accomplished by utilizing a simple coupling reaction of stable 2-pyridylzinc bromides and 3-pyridylzinc bromides.
Reuben D. Rieke, Seung-Hoi Kim
doaj   +1 more source

Transportation Development Division, Active Transportation Section, April 1, 2014

open access: yes, 2014
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on April 11, 2014)Mode of ...

core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Rosuvastatina e ciprofibrato no tratamento da dislipidemia em pacientes com HIV Rosuvastatin and ciprofibrate in the treatment of dyslipidemia in patients with HIV

open access: yesArquivos Brasileiros de Cardiologia, 2012
FUNDAMENTO: A dislipidemia secundária à terapia antirretroviral potente nos pacientes com HIV está associada à significativa elevação da morbimortalidade cardiovascular por doença aterosclerótica, sendo, portanto, necessário tratamento imediato e eficaz.
Hamilton Domingos   +5 more
doaj  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Budget impact analysis of alternative strategies for initiating antiretroviral therapy in Nigeria

open access: yesMediterranean Journal of Pharmacy and Pharmaceutical Sciences
The World Health Organization (WHO) has recently made recommendations for treating all Human Immunodeficency Virus (HIV/AIDS) patients irrespective of their immune status.
Halima B. Giwa
doaj   +1 more source

Intractable and highly active relapsing multiple sclerosis – role of alemtuzumab

open access: yes, 2015
Divyanshu Dubey,1 Christopher A Cano,1 Olaf Stuve1–3 1Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, 2Neurology Section, VA North Texas Health Care System, Medical Service, Dallas, TX, USA ...
Cano CA, Dubey D, Stuve O
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Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Determinants of immunological failure among clients on the first line treatment with highly active antiretroviral drugs in Dar es Salaam, Tanzania

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2014
Objective: To determine socio-cultural, demographic and highly active antiretroviral therapy (HAART) program-related factors associated with immunological failure (IF) among clients on HAART in Dar es Salaam care and treatment clinics.
Anthony Kapesa   +5 more
doaj   +1 more source

The neuro-developmental profile of preschool-aged children receiving highly active antiretroviral therapy in Johannesburg, South Africa

open access: yes, 2015
The neuro-developmental profile of preschool-aged children receiving highly active antiretroviral therapy in Johannesburg South Africa.
Hilburn, N.
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