Results 61 to 70 of about 8,362,360 (307)
Evaluation of Adherence to Highly Active Antiretroviral Therapy
Archives of Internal Medicine, 2001 This work has been supported by project 2109/00 from the Fundación para la Investigación y la Prevención del Sida en España (FIPSE), Madrid, Spain.
Martín Fernández, Jesús +3 more
openaire +3 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Transportation Development Division, Active Transportation Section
, 2015 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on March 9, 2015).Mode of ...
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Brazilian Journal of Infectious DiseasesInformation about resistance profile of darunavir (DRV) is scarce in Brazil. Our objectives were to estimate the prevalence of DRV resistance mutations in patients failing protease inhibitors (PI) and to identify factors associated with having more DRV ...
Jose E Vidal +5 more
doaj +1 more source
Highly active CeO2 hollow-shell spheres with Al doping
, 2017 Metal oxide hollow structures are of great interest in many current and emerging areas of technology. This paper presents a facile and controlled protocol for the synthesis of Al-doped CeO2 hollow-shell spheres (CHS), where the dopant confers enhanced ...
Li, Yanhui +15 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A highly active “NiO-on-Au”Surface Architecture for CO Oxidation
, 2013 A highly active “NiO-on-Au”Surface Architecture for CO ...
包信和, 许学俊, 傅强, 郭晓光
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An active viscoelastic metamaterial for isolation applications
, 2014 Metamaterials are of interest due to their ability to produce novel acoustic behaviour beyond that seen in naturally occurring media. Of particular interest is the appearance of band gaps which lead to very high levels of attenuation within narrow ...
Reynolds, Matthew, Daley, Stephen
core +1 more source