Results 241 to 250 of about 5,670,099 (298)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Discovery of highly active kynureninases for cancer immunotherapy through protein language model. [PDF]

open access: yesNucleic Acids Res
Eom H   +12 more
europepmc   +1 more source

Synthesis of Bis(diimino)palladium Nanosheets as Highly Active Electrocatalysts for Hydrogen Evolution. [PDF]

open access: yesChemistry
Maeda H   +11 more
europepmc   +1 more source

A thermostable and highly active fungal GH3 β-glucosidase generated by random and saturation mutagenesis. [PDF]

open access: yesProc Jpn Acad Ser B Phys Biol Sci
Matsuzaki C   +8 more
europepmc   +1 more source

Highly active nitro-aromatic antiparasitic drugs.

open access: yesDie Pharmazie, 1982
Jefford, Charles   +3 more
openaire   +2 more sources

Design of a Highly Active Peptide Inhibitor of Farnesyltransferase and Its Protective Effect Against Acute Liver Failure. [PDF]

open access: yesDrug Des Devel Ther
Huang CL   +8 more
europepmc   +1 more source

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