Results 261 to 270 of about 8,362,360 (307)
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Highly active neurons emerging in vitro
Journal of Neurophysiology, 2021The overdispersion of neuronal activity levels can often be attributed to very few neurons exhibiting extremely high firing rates, but due to technical difficulty, no studies have examined how these outliers are selected during development and whether they are maintained over time.
Mami Okada +5 more
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Highly activated, silicone entrapped, lipase
Chemical Communications, 2003Lipase is more reactive in silicone oil or silicone elastomers than in hydrocarbons, and can be formulated into convenient, active, immobilized enzyme packages.
Amro, Ragheb +2 more
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A highly active synthetic mammalian retrotransposon
Nature, 2004LINE-1 (L1) elements are retrotransposons that comprise large fractions of mammalian genomes. Transcription through L1 open reading frames is inefficient owing to an elongation defect, inhibiting the robust expression of L1 RNA and proteins, the substrate and enzyme(s) for retrotransposition.
Jeffrey S, Han, Jef D, Boeke
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Highly active, lipase silicone elastomers
Biomaterials, 2005Lipase Candida rugosa was entrapped in silicone rubber via condensation-cure room temperature vulcanization of silanol-terminated poly(dimethylsiloxane) with tetraethyl orthosilicate as a crosslinker, to give a highly active silicone-enzyme elastomer.
Amro M, Ragheb +2 more
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Highly efficient catalase activity of metallocorroles
Chemical Communications, 2010The iron(iii) complex of a bipolar and amphiphilic corrole, which binds strongly to proteins and undergoes protein-mediated cellular uptake, catalyzes the decomposition of hydrogen peroxide faster (k(cat) = 6400 M(-1) s(-1)) and more efficiently (turnover frequency >120 s(-1)) than previously reported synthetic compounds with catalase-like activity.
Atif, Mahammed, Zeev, Gross
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The secrets of highly active older adults
Journal of Aging Studies, 2013Although physical activity is a recognized component in the management of many chronic diseases associated with aging, activity levels tend to progressively decline with increasing age (Manini & Pahor, 2009; Schutzer & Graves, 2004). In this article we examine the key factors that facilitate physical activity in highly active community-dwelling older ...
Thea, Franke +4 more
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Highly active antimycobacterial derivatives of benzoxazine
Bioorganic & Medicinal Chemistry, 2010New 3-(4-alkylphenyl)-4-thioxo-2H-1,3-benzoxazine-2(3H)-ones and 3-(4-alkylphenyl)-2H-1,3-benzoxazine-2,4(3H)-dithiones were synthesized. The compounds were tested for in vitro antimycobacterial activity against Mycobacterium tuberculosis, Mycobacterium avium and two strains of Mycobacterium kansasii.
Eva, Petrlíková +7 more
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Phosphorylation Organocatalysts Highly Active by Design
Organic Letters, 2020The activity of nucleophilic organocatalysts for alcohol/phenol phosphorylation was enhanced through attaching oligoether appendages to a benzyl substituent on imidazole- or aminopyridine-based active units, presumably because of stabilizing n-cation interactions of the ethereal oxygens with the positively charged aza-heterocycle in the catalytic ...
Amit Fallek +4 more
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Science, 2007
The observation that biological activity in eddies can be very high may help explain why measurements of ocean productivity have varied widely.
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The observation that biological activity in eddies can be very high may help explain why measurements of ocean productivity have varied widely.
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HIGHLY ACTIVE ANTICANCER CURCUMIN ANALOGUES
2007Curcumin, a compound in the human food supply, represents a near-perfect starting point for drug discovery. Consequently, a number of research groups have taken the natural product as a starting point to prepare and biologically evaluate a wide variety of curcumin analogues.
Cara A, Mosley +2 more
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