Results 51 to 60 of about 5,670,099 (298)

Highly Active, Entirely Biobased Antimicrobial Pickering Emulsions

ChemMedChem, 2021
AbstractWe present the development of surfactant‐free, silica‐free and fully biobased oil‐in‐water antimicrobial Pickering emulsions, based on the self‐assembly of β‐cyclodextrin and phytoantimicrobial oils (terpinen‐4‐ol or carvacrol). Undecylenic acid (UA), derived from castor oil, can be used as bio‐based drug to treat fungal infection, but is less ...
Leclercq, Loïc, Tessier, Jérémie, Nardello-Rataj, Véronique, Schmitzer, Andreea‐ruxandra   +3 more
openaire   +5 more sources

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Case report: A highly active refractory myasthenia gravis with treatment of telitacicept combined with efgartigimod

Frontiers in Immunology
There is always a lack of effective treatment for highly active refractory generalized myasthenia gravis (GMG). Recently, telitacicept combined with efgartigimod significantly reduces circulating B cells, plasma cells, and immunoglobulin G, which brings ...
Chaoyue Zhang, Yangtao Lin, Qianjin Kuang, Hongjin Li, Qilong Jiang, Xiaojun Yang   +5 more
doaj   +1 more source

Antiretroviral agents against human immunodeficiency virus

DST, 2022
Introduction: Since its discovery in the 1980s, the human immunodeficiency virus (HIV) has been the target of many studies. Nowadays, estimates show that 36.7 million people are infected with HIV worldwide.
Ingrid Barcelos de Oliveira, Claudio Cesar Cirne Santos, Izabel Christina Nunes de Palmer Paixão, Caroline de Souza Barros, Rosa Teixeira Pinho   +4 more
doaj  

Gemcitabine, Docetaxel, Melphalan, Carboplatin as Part of Sequential Cycles of High‐Dose Chemotherapy With Autologous Hematopoietic Stem‐Cell Rescue for Multiply Relapsed/Refractory Pediatric Germ Cell Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost, Olayinka Okeleji, Amr Elgehiny, Douglas Harrison, Cynthia Herzog, Jeremy Connors, Demetrios Petropoulos, Priti Tewari, Dristhi Ragoonanan, Yago Nieto, Irtiza N. Sheikh   +10 more
wiley   +1 more source

Development and validation of a clinical score for prognosis stratification in patients requiring antiretroviral therapy in sub-Saharan Africa: a prospective open cohort study

The Pan African Medical Journal, 2011
BACKGROUND: Mortality rates among patients initiating antiretroviral therapy (ART) in sub-Saharan Africa continue high. Also HIV treatment services from the region are affronting the challenges of been attending more patients than never. In this scenario,
Rivero Gerardo, Perez Dayana
doaj   +1 more source

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender, Lauren Pommert, Lori R. Backus, Andrea Bidwell, Courtney Blank, Erin H. Breese, Karen C. Burns, Adam Lane, Lynn H. Lee, Benjamin Mizukawa, Robin E. Norris, Maureen M. O'Brien, Daniel Peck, Christine Phillips, Thomas D. Ryan, Jennifer Young, Michael Absalon, John P. Perentesis   +17 more
wiley   +1 more source

Bone Disease in HIV: Need for Early Diagnosis and Prevention

Life
The transformation of HIV into a manageable chronic condition has unveiled new clinical challenges associated with aging-related pathologies, including bone disease. This review explores the intricate relationship between HIV, antiretroviral therapy (ART)
Georgios Schinas, Ioannis Schinas, Georgios Ntampanlis, Eleni Polyzou, Charalambos Gogos, Karolina Akinosoglou   +5 more
doaj   +1 more source

Incidence of opportunistic diseases after the “treat all” strategy: 10 years cohort for HIV [PDF]

Brazilian Journal of Biology
High active anti-retroviral therapy (HAART) has improved the life expectancy of people living with HIV/AIDS (PLWHA) and reduced the development of opportunistic diseases, supporting a strategy introduced in 2014, which sought to enhance prevention with ...
R. O. Nascimento, B. M. Minan, L. C. G. C. Duarte, C. M. B. R. G. Panjwani, S. M. S. Ferreira, G. M. França   +5 more
doaj   +1 more source

Theoretical Study on Highly Active Bifunctional Metalloporphyrin Catalysts for the Coupling Reaction of Epoxides with Carbon Dioxide [PDF]

, 2016
Highly active bifunctional metalloporphyrin catalysts were developed for the coupling reaction of epoxides with CO2 to produce cyclic carbonates. The bifunctional catalysts have both quaternary ammonium halide groups and a metal center.
Ahmadi, Aida, Becke, Castro-Gómez, Chen, Chen, Cokoja, Cokoja, Comerford, D'Elia, Darensbourg, Ema, Ema, Ema, Foltran, Jin, Kielland, Kruper, Lee, Li, Li, Liu, Ma, Maeda, Maeda, Maeda, Martín, Paddock, Qin, Reed, Reed, Rocha, Stewart, Sun, Tlili, Tomasi, Tsuji, Wang, Wang, Wang, Whiteoak, Whiteoak   +41 more
core   +1 more source