Results 91 to 100 of about 112,497 (212)

HindIIIpolymorphism in the DCC gene

Nucleic Acids Research, 1991
P, Devilee, M, van Vliet, K R, Cho, B, Vogelstein   +3 more
openaire   +3 more sources

New Integrative Vectors Increase Agrobacterium rhizogenes Transformation and Help Characterise Roles for Soybean GmTML Gene Family Members

Plant, Cell &Environment, EarlyView.
ABSTRACT Hairy‐root transformation is widely used to generate transgenic plant roots for genetic functional characterisation studies. However, transformation efficiency can be limited, largely due to the use of binary vectors. Here, we report on the development of novel integrative vectors that significantly increase the transformation efficiency of ...
Huanan Su, Mengbai Zhang, Estelle B. Grundy, Brett J. Ferguson   +3 more
wiley   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

Transfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike, Albert Bondt, Douwe Schulte, Rien Leuvenink, Dirk Jan Mons, Peter C. Ligthart, E. Joanne T. Verweij, AFRICARhE Consortium, Enrico Lopriore, E. J. T. Joanne Verweij, Tienke Vermeiden, Thomas van den Akker, C. Ellen van der Schoot, Derek P. de Winter, Renske van Oever, Abera Kenay Tura, Tadesse Gure, Assefa Desalew, Tewodros Tesfa, Konjit Eshetu, Jeremia Pyuza, Rafiki N. Mjema, Priscus John Mapendo, Jeremiah John Hhera, Bariki Mchome, Patricia Swai, Blandina T. Mmbaga, Aisa Shayo, Peter Moons, Kondwani Kawaza, Luis Gadama, Albert J. R. Heck, C. Ellen van der Schoot, Gestur Vidarsson   +33 more
wiley   +1 more source

Detección de portadoras de hemofilia “A” en familias con riesgo mediante análisis de ligamiento en tres poblaciones de Colombia

Iatreia, 2010
El análisis de ligamiento ha sido ampliamente usado para la detección de portadoras y el consejo genético de familias afectadas con Hemofilia A. Sin embargo, existe poco conocimiento sobre las frecuencias de heterocigotos (heterocigosidad) para los ...
Guillermo Barreto, Fabián Andrés Franco, Carolina Cortes, Sandra Patricia Ocampo   +3 more
doaj  

Evaluation of Loss of the Y Chromosome in Peripheral Blood as a Biomarker for Prostate Cancer

The Prostate, Volume 86, Issue 6, Page 665-675, May 2026.
ABSTRACT Background Prostate cancer (PCa) is the most common malignant tumor in men, but the widely used prostate‐specific antigen (PSA) test has limited diagnostic accuracy. Research proposes that the loss of the Y chromosome (LOY) may affect the occurrence and development of prostate cancer, aiming to assess its potential as a diagnostic biomarker to
Jun Lu, Yan Lu, Takuro Kobayashi, Tsuyoshi Hachiya, Haruhiko Wakita, Yiming Jin, Yasunari Tanaka, Yoshihiro Ikehata, Masayoshi Nagata, Hisamitsu Ide, Shigeo Horie   +10 more
wiley   +1 more source

β-globin haplotypes in normal and hemoglobinopathic individuals from Reconcavo Baiano, State of Bahia, Brazil

Genetics and Molecular Biology, 2010
Five restriction site polymorphisms in the β-globin gene cluster (HincII-5'ε, HindIII-Gγ, HindIII-ªγ, HincII-'ψβ1 and HincII-3''ψβ1) were analyzed in three populations (n = 114) from Reconcavo Baiano, State of Bahia, Brazil. The groups included two urban
Wellington dos Santos Silva, Maria de Nazaré Klautau-Guimarães, Cesar Koppe Grisolia   +2 more
doaj  

Human parathyroid hormone-like peptide gene: HindIII and Taql RFLPs [PDF]

Nucleic Acids Research, 1990
G N, Hendy, D, Goltzman
openaire   +2 more sources

Tn‐seq of Thermus thermophilus Genome Reveals Unexpected Tolerance to Insertions in Bacterial Common Essential Genes

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Tn‐seq analysis of Thermus thermophilus genome reveals insertions in almost all genes, this is, there is no clear discrimination of essential genes. A similar result has not been reported in other Tn‐seq analysis of bacterial genomes so far. The polyploidy of the Thermus genome could explain the apparent non‐essentiality of key genes.
Cristina L. Gómez‐Campo, Marc Gost, Bruna Fernanda Silva de Sousa, Laura Álvarez, José Berenguer, Modesto Redrejo‐Rodríguez, Mario Mencía   +6 more
wiley   +1 more source

Human Citrate Synthase Post‐Translational Modification Mimics and Molecular Dynamic Simulations Demonstrate Attenuation of Acetyl‐CoA/CoA Binding

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 4, Page 883-892, April 2026.
ABSTRACT Human citrate synthase (hCS) is a mitochondrial enzyme that catalyzes the aldol condensation of acetyl coenzyme A (AcCoA) to oxaloacetate to form citrate in the TCA cycle. CS activity is important for aerobic exercise performance and basic metabolic function as a housekeeping enzyme.
Noah Shackelford, Zach Zavodny, Nathan Fancher, Michael A. Moxley   +3 more
wiley   +1 more source

Branched‐Chain Amino Acids Mediate the Regulation of SACE_Lrp on the Aminotransferase IlvE Involved in Erythromycin Biosynthesis in Saccharopolyspora erythraea

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
This study demonstrated that SACE_Lrp binds to the ilvE promoter in a BCAA‐dependent manner, and BCAAs addition results in a higher increase of ilvE transcription and erythromycin production in mutant ΔSACE_Lrp than in the original strain S. erythraea A226.
Xinlu Cai, Lijuan Tang, Yinuo Liu, Youquan Zou, Xueyan Li, Haoyang He, Youya Tang, Endong Yang, Buchang Zhang, Jing Liu   +9 more
wiley   +1 more source