Results 161 to 170 of about 161,067 (287)

A comparative molecular approach to mesodermal patterning in basal deuterostomes: the expression pattern of Brachyury in the enteropneust hemichordate Ptychodera flava [PDF]

open access: yes, 1999
This work concerns the formation of mesoderm in the development of an enteropneust hemichordate, Ptychodera flava, and the expression of the Brachyury gene during this process. Brachyury expression occurs in two distinct phases.
Cameron, R. Andrew   +4 more
core  

Optimized ACE2‐Fc fusion proteins with picomolar neutralization activity against highly evolved SARS‐CoV‐2 variants

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract The rapid evolution of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has compromised the efficacy of many authorized monoclonal antibody products. This highlights the need for alternative strategies, especially for vulnerable populations such as immunocompromised individuals.
Ferran Abancó   +16 more
wiley   +1 more source

Associating protein residues in the literature with structural data

open access: yesActa Crystallographica Section D, Volume 82, Issue 2, Page 113-125, February 2026.
A software tool is introduced for associating text mentions of protein residues with their respective residues in a protein structure, with display in a molecular viewer.Protein structures are crucial in understanding the function, mechanism and disease‐causing variants of proteins within any living cell.
Melanie Vollmar   +6 more
wiley   +1 more source

Roles of Alp and Prt Regulons in the Response of Pseudomonas aeruginosa to UV‐C Light

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Our results show that LexA‐regulated genes are the first to be induced after DNA damage, while autolysis functions controlled by the Alp system are the last. Death by UV is mediated primarily by Alp or Prt systems, depending on the Pseudomonas aeruginosa subline. ABSTRACT UV light is a well‐studied environmental DNA damaging agent.
Marina R. B. Fonseca   +6 more
wiley   +1 more source

Synaptic Vesicle Glycoprotein 2A Suppresses Amyloidogenesis Beyond Its Synaptic Role: A Novel Mechanism Disrupting BACE1 Binding and Altering APP Localization

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Synaptic vesicle glycoprotein 2A, the newly identified APP‐binding protein, reduces amyloid‐β plaque deposition in Alzheimer's disease by suppressing the amyloidogenic pathway through inhibition of BACE1‐APP interaction and alteration of APP endosomal‐lysosomal localization.
Xiaoling Wang   +11 more
wiley   +1 more source

Late Stage Mannan Metabolism in Cellvibrio japonicus Requires the Combined Action of a Mannosyl‐Glucose Phosphorylase and a Mannobiose Epimerase

open access: yesMolecular Microbiology, Volume 125, Issue 2, Page 173-184, February 2026.
Model for the non‐PTS utilization of manno‐oligosaccharides by Cellvibrio japonicus. The Mgp130A and EpiA enzymes are essential for the utilization of mannose residues. ABSTRACT Manno‐oligosaccharides and their metabolism play important roles in gut health, pharmaceutical development, and renewable chemical production.
Jessica K. Novak, Jeffrey G. Gardner
wiley   +1 more source

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