Results 51 to 60 of about 56,866 (307)

Radiographic Morphometric Measurements of the Donkey’s Distal Hind Limb

Animals
Morphometric measurements of the toe serve as a reference for the objective assessment of the presence of a pathological condition and as a guide for the correct trimming of the hooves.
Kyra Schaus, Juliana Wacker, Anabell Jandowsky, Kathrin Büttner, Michael Röcken, Claus Peter Bartmann   +5 more
doaj   +1 more source

Inhibiting myostatin signaling partially mitigates structural and functional adaptations to hindlimb suspension in mice

npj Microgravity, 2023
Novel treatments for muscle wasting are of significant value to patients with disease states that result in muscle weakness, injury recovery after immobilization and bed rest, and for astronauts participating in long-duration spaceflight.
Andrea M. Hanson, Mary H. Young, Brooke C. Harrison, Xiaolan Zhou, H. Q. Han, Louis S. Stodieck, Virginia L. Ferguson   +6 more
doaj   +1 more source

Inhibition of myeloperoxidase increases revascularization and improves blood flow in a diabetic mouse model of hindlimb ischaemia

Diabetes & Vascular Disease Research, 2020
Objective: Diabetes mellitus is a significant risk factor for peripheral artery disease. Diabetes mellitus induces chronic states of oxidative stress and vascular inflammation that increase neutrophil activation and release of myeloperoxidase.
Dorothee Weihrauch, Dustin P Martin, Deron Jones, John Krolikowski, Janine Struve, Stephen Naylor, Kirkwood A Pritchard   +6 more
doaj   +1 more source

Cordymin alleviates osteoporosis induced by hindlimb unloading via regulating the gut - microelements -bone axis --for non-clinical studies

BMC Musculoskeletal Disorders, 2023
Introduction The purpose of this study was to evaluate the protective effects of cordymin on osteoporosis induced by hindlimb unloading(HLU) in rats and whether cordymin can prevent bone loss from HLU.
Wei Qi, Tiancheng Ma, Yufei Ji, Hong Jia, Qiang Sun, Dawei Zhang   +5 more
doaj   +1 more source

Functional analysis of a first hindlimb positioning enhancer via Gdf11 expression

Frontiers in Cell and Developmental Biology
During the early development of tetrapods, including humans, the embryonic body elongates caudally once the anterior-posterior axis is established.
Seiji Saito, Utsugi Kanazawa, Ayana Tatsumi, Atsuo Iida, Tatsuya Takemoto, Takayuki Suzuki   +5 more
doaj   +1 more source

Pharmacological and Genetic Inhibition of PD-1 Demonstrate an Important Role of PD-1 in Ischemia-Induced Skeletal Muscle Inflammation, Oxidative Stress, and Angiogenesis

Frontiers in Immunology, 2021
Angiogenesis is an important process under both physiological and pathophysiological conditions. Here we investigated the role and the underlying mechanism of PD-1 in hindlimb ischemia-induced inflammation and angiogenesis in mice.
Xiaoguang Liu, Xinyu Weng, Xinyu Weng, Weihua Xiao, Xin Xu, Yingjie Chen, Yingjie Chen, Peijie Chen   +7 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Rewiring of hindlimb corticospinal neurons after spinal cord injury [PDF]

, 2010
Little is known about the functional role of axotomized cortical neurons that survive spinal cord injury. Large thoracic spinal cord injuries in adult rats result in impairments of hindlimb function.
Mueggler, T, Markus Rudin, Ghosh, A, Gullo, M, Florent Haiss, Haiss, F, Schwab, M E, Martin E Schwab, Matthias T Wyss, Rudin, M, Thomas Mueggler, Schneider, R, Christof Baltes, Miriam Gullo, Baltes, C, Weber, B, Esther Sydekum, Sydekum, E, Regula Schneider, Arko Ghosh, Bruno Weber, Wyss, M T   +21 more
core   +1 more source

Regional Lymphatic Inclusion in Orthotopic Hindlimb Transplantation: Establishment and Assessment of Feasibility in a Rodent Model. [PDF]

, 2020
Background The lymphatic system may play an important role in local immunomodulation in vascularized composite allotransplantation (VCA). Currently, there is no standardized VCA model that includes the regional draining lymphatic tissue.
Leckenby, Jonathan Ian, Olariu, Radu, Lese, Ioana, Leclère, Franck M., Taddeo, Adriano, Vögelin, Esther, Gayanayake, Thusitha, Banz, Yara, Constantinescu, Mihai A.   +8 more
core   +1 more source

CT-based optimization of hindlimb muscle measurement levels and development of a hindlimb muscle condition score in dogs

Frontiers in Veterinary Science
IntroductionObjective assessment of hindlimb skeletal muscles in dogs remains challenging in small animal practice. This study aimed to use computed tomography (CT) to characterize hindlimb muscle distribution, identify optimal measurement levels, and ...
Sukchan Yun, Seri Hong, Yeonjae Lee, Kija Lee, Sooyoung Choi, Daji Noh   +5 more
doaj   +1 more source