Results 61 to 70 of about 61,808 (305)

Heat stress attenuates skeletal muscle atrophy in hindlimb-unweighted rats

, 2000
This study tested the hypothesis that elevation of heat stress proteins by whole body hyperthermia is associated with a decrease in skeletal muscle atrophy induced by reduced contractile activity (i.e., hindlimb unweighting). Female adult rats (6 mo old)
Haydar A. Demirel, Junichiro Aoki, Stephen L. Dodd, Hisashi Naito, Scott K. Powers, Takao Sugiura   +5 more
core   +2 more sources

Comparative study of peroneus tertius muscle in pigs based on origin, course, insertion and innervation

Folia Morphologica
BACKGROUND: That the peroneus tertius muscle (PT) is a separate entity has been long debated. PT has been variously reported to be part of the extensor digitorum longus muscle, part of the extensor digitorum brevis, or a separate muscle.
Yutaro Natsuyama, Ting Yang, Rujia Li, Kazuyuki Shimada, Shunichi Uetake, Ke Ren, Yasuko Kamikawa, Konosuke Tokita, Ryuhei Kojima, Masahiro Itoh, Shuang-Qin Yi   +10 more
doaj   +1 more source

Pulsatility Index as a Novel Parameter for Perfusion in Mouse Model of Hindlimb Ischemia

Cellular Physiology and Biochemistry, 2018
Background/Aims: In clinical settings, the pulsatility index (PI) has become a widely used tool for monitoring obstetrics or other vascular diseases. It is based on the maximum Doppler shift waveform derived from ultrasonography.
Hairong Xu, Shan Lu, Lexi Ding, Liangkun Lyu, Zejun Ma, Qiulun Lu   +5 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Effect of Rehabilitation in a Dog with Delayed Recovery following TPLO: A Case Report

Animals, 2023
A 7-year-old neutered Maltese dog weighing 5.1 kg was presented, with a tibial plateau-leveling osteotomy (TPLO) on the right hindlimb 42 days prior. The patient’s right hind limb showed lameness, intermittent limping, and atrophy, and the patient had ...
Shin-Ho Lee, Jae-Hyeon Cho, Chung-Hui Kim, Dongbin Lee   +3 more
doaj   +1 more source

Hindlimb unweighting for 2 weeks alters physiological properties of rat hindlimb motoneurones

The Journal of Physiology, 2005
We sought to determine whether decreased neuromuscular use in the form of hindlimb unweighting (HU) would affect the properties of innervating motoneurones. Hindlimb weight‐bearing was removed in rats for a period of 2 weeks via hindlimb suspension by the tail.
Cormery, Bruno, Beaumont, Eric, Csukly, Kristina, Gardiner, Phillip   +3 more
openaire   +4 more sources

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Hindlimb IR enhances ChAT and CHT1 expression in the affected hindlimb and in the heart.

, 2013
(A) Compared with the right hindlimb (R), the left hindlimb subjected to IR had increased protein expression of ChAT and CHT1 in tissue samples isolated from quadriceps femoris muscle within 16 h ...
Yoshihiko Kakinuma (141355), Tatsuya Noguchi (297126), Takayuki Sato (253061), Tsuyoshi Akiyama (297120), Mikihiko Arikawa (297124), Kayo Okazaki (297122)   +5 more
core   +1 more source

Influence of androgen receptor in vascular cells on reperfusion following hindlimb ischaemia [PDF]

, 2016
AimsStudies in global androgen receptor knockout (G-ARKO) and orchidectomised mice suggest that androgen accelerates reperfusion of the ischaemic hindlimb by stimulating angiogenesis.
Wu, Junxi, Patrick W F Hadoke, Martin A. Denvir (326026), Junxi Wu (2736010), Agnieszka Korczak (2736007), Kaloyan Takov, Agnieszka Korczak, Wu Junxi, Junxi Wu, Denvir Martin A., Lee B. Smith (161960), Hadoke, Patrick W.F., Smith, Lee B., Takov Kaloyan, Patrick W. F. Hadoke (206485), Takov, Kaloyan, Kaloyan Takov (2736004), Korczak Agnieszka, Lee B Smith, Denvir, Martin A., Denvir, Martin A, Smith Lee B., Smith, Lee B, Hadoke, Patrick WF, Hadoke Patrick W. F., Martin A Denvir, Korczak, Agnieszka   +26 more
core   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source