Results 81 to 90 of about 61,808 (305)

An experimental model of ischemia in rabbit hindlimb [PDF]

Journal of Korean Medical Science, 2001
This study was performed to establish an experimental model of ischemia for the investigation of new treatment modality of limb-threatening ischemia. We produced ischemia in the hindlimbs of 8 New Zealand white rabbits. Under general anesthesia, the left femoral artery was exposed, freed, and excised from distal external iliac artery to proximal ...
J H, Hong, Y W, Bahk, J S, Suh, B K, Kwak, H J, Shim, J S, Kim, H S, Kim, Y H, Moon, S J, Kim, J W, Chung, J H, Park   +10 more
openaire   +2 more sources

Engineering Ultrastable Intrinsic Radicals: Graphene Quantum Dots With NIR‐II Emission for Dynamic Deep‐Tissue Bioimaging

Advanced Science, EarlyView.
Stable radicals are attractive for photonic and quantum information technologies but are often limited by instability. We stabilize intrinsic radicals in graphene quantum dots via 2D polymerization of perylene derivatives, where bilayer defect confinement suppresses quenching (100–500 K).
Qin Xu, Yijie Hou, Bingzhe Wang, Tesen Zhang, Yupeng Liu, Shuaiqi Li, Maohua Chen, Guichuan Xing, Dongbo Guo, Songnan Qu   +9 more
wiley   +1 more source

Dense distributed processing in a hindlimb scratch motor network

, 2014
In reduced preparations, hindlimb movements can be generated by a minimal network of neurons in the limb innervating spinal segments. The network of neurons that generates real movements is less well delineated.
Hounsgaard, Jørn Dybkjær, Guzulaitis, Robertas   +1 more
core   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

Near-Infrared Fluorescence Imaging Directly Visualizes Lymphatic Drainage Pathways and Connections between Superficial and Deep Lymphatic Systems in the Mouse Hindlimb

Scientific Reports, 2018
Since lymphedema rarely develops in the mouse hindlimb, the underlying mechanisms remain unclear. We herein investigated the resolution of chronic hindlimb lymphedema in mice using a Near-Infrared Fluorescence (NIRF) imaging system.
Yukari Nakajima, Kimi Asano, Kanae Mukai, Tamae Urai, Mayumi Okuwa, Junko Sugama, Toshio Nakatani   +6 more
doaj   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

Endochondral ossification of hindlimbs in embryonic development of Japanese Quail (Coturnix japonica)

Avian Research
The endochondral ossification of hindlimb is essential to a bird's ability to stand, walk and fly. Most hindlimb is ossified in the embryos before hatching in precocial birds.
Xuan Li, Yuxin Zhang, Hongfeng Zhao
doaj   +1 more source

NO-Dependent Mechanisms of Myosin Heavy Chain Transcription Regulation in Rat Soleus Muscle After 7-Days Hindlimb Unloading

Frontiers in Physiology, 2020
It is known that nitric oxide (NO) may affect myosin heavy chain (MyHC) isoform mRNA transcription in skeletal muscles. The content of NO in soleus muscles decreases during rat hindlimb unloading as well as slow MyHC mRNA transcription.
Kristina A. Sharlo, Inna I. Paramonova, Irina D. Lvova, Natalia A. Vilchinskaya, Anna E. Bugrova, Tatiana F. Shevchenko, Grigoriy R. Kalamkarov, Boris S. Shenkman   +7 more
doaj   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Rewiring of hindlimb corticospinal neurons after spinal cord injury

, 2010
Little is known about the functional role of axotomized cortical neurons that survive spinal cord injury. Large thoracic spinal cord injuries in adult rats result in impairments of hindlimb function.
Mueggler, T, Markus Rudin, Ghosh, A, Gullo, M, Florent Haiss, Haiss, F, Schwab, M E, Martin E Schwab, Matthias T Wyss, Rudin, M, Thomas Mueggler, Schneider, R, Christof Baltes, Miriam Gullo, Baltes, C, Weber, B, Esther Sydekum, Sydekum, E, Regula Schneider, Arko Ghosh, Bruno Weber, Wyss, M T   +21 more
core   +1 more source