Results 81 to 90 of about 56,651 (307)

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

open access: yesAdvanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu   +11 more
wiley   +1 more source

Rewiring of hindlimb corticospinal neurons after spinal cord injury

open access: yes, 2010
Little is known about the functional role of axotomized cortical neurons that survive spinal cord injury. Large thoracic spinal cord injuries in adult rats result in impairments of hindlimb function.
Mueggler, T   +21 more
core   +1 more source

Comparative hindlimb myology within the family Falconidae [PDF]

open access: yes, 2017
A characteristical feature of a raptors’ hindlimb is their strengthen musculature that aids gripping prey with their sharp talons. To trace specific anatomical modifications it is necessary to study closely related species, with this aim, the myology of ...
María Clelia Mosto   +1 more
core   +1 more source

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

open access: yesAdvanced Science, EarlyView.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong   +4 more
wiley   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng   +9 more
wiley   +1 more source

Is Hindlimb Morphology a Reliable Indicator of Theropod Clade Membership?

open access: yes
The morphology of the theropod hindlimbs is the subject of detailed scrutiny. Most of the current literature on theropod hindlimbs has focused on the biomechanical and ecological implications of their distinct morphologies, and usually tackle individual ...
Shane Wheatley (21497397)
core   +1 more source

NO-Dependent Mechanisms of Myosin Heavy Chain Transcription Regulation in Rat Soleus Muscle After 7-Days Hindlimb Unloading

open access: yesFrontiers in Physiology, 2020
It is known that nitric oxide (NO) may affect myosin heavy chain (MyHC) isoform mRNA transcription in skeletal muscles. The content of NO in soleus muscles decreases during rat hindlimb unloading as well as slow MyHC mRNA transcription.
Kristina A. Sharlo   +7 more
doaj   +1 more source

Coordination of the legs of a slow-walking cat

open access: yes, 1992
Cruse H, Warnecke H. Coordination of the legs of a slow-walking cat. Experimental Brain Research. 1992;89(1):147-156.On the basis of behavioural studies the influences that coordinate the movement of the legs of a slowly walking cat have been ...
Warnecke, H., Cruse, Holk
core   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

open access: yesAdvanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang   +5 more
wiley   +1 more source

Genetic basis of hindlimb loss in a naturally occurring vertebrate model

open access: yesBiology Open, 2016
Here we genetically characterise pelvic finless, a naturally occurring model of hindlimb loss in zebrafish that lacks pelvic fin structures, which are homologous to tetrapod hindlimbs, but displays no other abnormalities.
Emily K. Don   +12 more
doaj   +1 more source

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