Results 131 to 140 of about 492,458 (242)
Enhancer Rewiring Orchestrates Inflammation and Loss of Cell Identity During Muscle Stem Cell Aging
Aging Cell, Volume 25, Issue 1, January 2026.A comprehensive multi‐omic profiling of murine muscle stem cells across three ages and both sexes reveals extensive enhancer and 3D genome rewiring, concomitant with increased inflammation, lineage drift, loss of quiescence, and reduced myogenic potential.
Changyou Shi +17 more
wiley +1 more source
Age‐Associated Dysregulation of Postsynaptic Mitochondria Perturbs Reinnervation Kinetics
Aging Cell, Volume 25, Issue 1, January 2026.We show that aging results in postsynaptic mitochondrial loss at the neuromuscular junction and impaired muscle reinnervation. In vivo CRISPR knockout of mitochondrial genes, CHCHD10 and CHCHD2, in young muscles led to fragmented endplates, aberrant innervation, and impaired transcriptional maturation of sub‐synaptic myonuclei during regeneration ...
Steve D. Guzman +8 more
wiley +1 more source
Effects of hindlimb suspension and recovery on rat slow soleus muscle.
, 1994 Yasuharu Oishi +2 more
openalex +1 more source
Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health
British Journal of Pharmacology, Volume 183, Issue 1, Page 40-56, January 2026.Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue +7 more
wiley +1 more source
Establishment and Validation of a C57BL/6J Mouse Model for Melasma
Cell Proliferation, Volume 59, Issue 1, January 2026.A melasma‐like mouse model was established in C57BL/6J mice using a combination of UVB irradiation, progesterone administration, and chronic psychological stress. This model replicates key clinical features and biomarker alterations observed in human melasma. Importantly, it is fundamentally distinct from UV‐induced post‐inflammatory hyperpigmentation (
Wenzhu Wang +9 more
wiley +1 more source
Fatigability and blood flow in the rat gastrocnemius-plantaris-soleus after hindlimb suspension [PDF]
, 1992 Kerry S. McDonald +2 more
openalex +1 more source
Equine Veterinary Journal, Volume 58, Issue 1, Page 230-242, January 2026.Abstract Background Icelandic horses are valued for their additional gaits, but assessing lameness in this breed can be challenging. Pelvic (P) vertical movement asymmetries, differences (D) in minimum (min)/maximum (max) position, are used to quantify impact (PDmin) and push‐off (PDmax) hindlimb lameness during the trot, but no established parameters ...
Marie Rhodin +7 more
wiley +1 more source
Hydrostatic Pressures in Lymphatic Networks of the Mouse
Microcirculation, Volume 33, Issue 1, January 2026.ABSTRACT Objective Current research on the lymphatic system makes nearly exclusive use of mouse models because that species is highly amenable to genetic manipulation. However, the lack of information about intraluminal hydrostatic pressures in mouse lymphatic networks limits the ability of investigators, for both in vivo and ex vivo studies, to ...
Michael J. Davis
wiley +1 more source
Neuromotor changes in postural control following bed rest
The Journal of Physiology, Volume 604, Issue 2, Page 761-782, 15 January 2026.Abstract figure legend Prolonged bed rest (BR) (both horizontal and head‐down tilt) leads to neuromotor adaptations that impair postural control. Structural and functional changes occur in the brain, including a reduction in grey and white matter volume, alterations in functional connectivity, and shifts in cerebrospinal fluid distribution.
Ramona Ritzmann +4 more
wiley +1 more source