Results 201 to 210 of about 492,458 (242)

Development of patellofemoral osteoarthritis with knee joint malalignment and lateral patellar dislocation after hindlimb suspension in growing rats

Journal of Orthopaedic Research
Knee malalignment is a risk factor for patellar instability and patellofemoral osteoarthritis (PFOA), but etiologies remain unknown. We investigated the potential effects of decreased weight loading during growth on knee alignments and patellofemoral (PF)
J. Ozawa, Airi Ikeda, Marina Kanehara, Hideki Moriyama, A. Kaneguchi   +4 more
semanticscholar   +1 more source

Age effects on rat hindlimb muscle atrophy during suspension unloading

Journal of Applied Physiology, 1990
Disuse can induce numerous adaptive alterations in skeletal muscle. In the present study the effects of hindlimb unloading on muscle mass and biochemical responses were examined and compared in adult (450 g) and juvenile (200 g) rats after 1, 7, or 14 days of whole body suspension.
J M, Steffen, R D, Fell, T E, Geoghegan, L C, Ringel, X J, Musacchia   +4 more
openaire   +2 more sources

Changes in rat atrial ANF granules induced by hindlimb suspension

Regulatory Peptides, 1994
It is well known that the heart releases a factor called ANF (atrial natriuretic factor) or ANP (atrial natriuretic peptide) capable of inducing rapid diuretic and natriuretic actions. This factor is stored in secretory granules mainly located in myocytes in both atria.
X, Holy, E, Zerath, A, Francois, P, Facy, A, Malouvier, C, Nogues   +5 more
openaire   +2 more sources

Models of disuse: a comparison of hindlimb suspension and immobilization

Journal of Applied Physiology, 1986
The effects of 1 and 2 wk of hindlimb suspension (HS) on rat skeletal muscle function were determined and the results compared with those obtained previously with hindlimb immobilization (HI). Both models of disuse (HS and HI) primarily affected slow-twitch muscle. Each decreased the isometric twitch duration in the slow-twitch soleus; however, the HS-
Fitts, Robert H., Metzger, Joseph Mark, Riley, Denise A., Unsworth, B. R.   +3 more
openaire   +3 more sources

Activity influences on soleus muscle myosin during rodent hindlimb suspension

Journal of Applied Physiology, 1987
This study examined the effect of stationary ground support (2 and 4 h/day) and uphill running (1.5 h/day, 20 m/min, 30% grade) activity patterns on soleus muscle atrophy and slow myosin loss during 4 wk of rodent hindlimb unweighting by tail suspension. We also examined the effect of uphill running during the last 4 wk of an 8-wk hindlimb unweighting
D B, Thomason, R E, Herrick, K M, Baldwin   +2 more
openaire   +2 more sources

(−)-Epicatechin Attenuates Degradation of Mouse Oxidative Muscle Following Hindlimb Suspension

Journal of Strength and Conditioning Research, 2016
The purpose of this study was to conduct a 14-day hindlimb suspension (HS) with and without (-)-epicatechin supplementation to determine whether (-)-epicatechin treatment can attenuate the loss in muscle degradation, angiogenesis, and mitochondrial signaling in oxidative skeletal muscle. Adult mice were randomized into 3 groups: (a) control (C); (b) HS
Icksoo, Lee, Maik, Hüttemann, Moh H, Malek   +2 more
openaire   +2 more sources

Running during recovery from hindlimb suspension induces transient muscle injury

Journal of Applied Physiology, 1990
The objectives were to study morphological adaptations of soleus muscle to decreased loading induced by hindlimb suspension and the effect of run training during the subsequent recovery period. Adult female Wistar rats were kept for 28 days with hindlimbs suspended.
C E, Kasper, T P, White, L C, Maxwell
openaire   +2 more sources

A simple hindlimb suspension apparatus.

Aviation, space, and environmental medicine, 1993
This paper describes the assembly of a simple, inexpensive apparatus for application of the hindlimb suspension model to studies of the effects of unloading on mammalian physiology. Construction of a cage and suspension assembly is described using materials that can be obtained from most hardware stores.
E, Park, E, Schultz
openaire   +1 more source

Effects of Growth hormone on rat skeletal muscle after hindlimb suspension

European Journal of Applied Physiology and Occupational Physiology, 1994
To examine the effects of growth hormone (GH) on the preferential atrophy of the soleus muscle (SOL) occurring after hindlimb suspension (HS), two groups of male rats received daily injections of 2 IU.kg-1 body mass of recombinant human growth hormone (rhGH). Rats were either suspended by the tail for 21 days (HS-GH, n = 5) or nonsuspended (C-GH, n = 5)
A X, Bigard, F, Lienhard, D, Merino, B, Serrurier, C Y, Guezennec   +4 more
openaire   +2 more sources

Pressure gradients and transport in the murine femur upon hindlimb suspension

Bone, 2006
Interstitial fluid flow (IFF) is important in a number of processes, including stimulation of cells and nutrient and waste transport. In bone, it arises from the vascular pressure gradient between the medullary cavity and the lymphatic drainage at the periosteal surface and is enhanced by mechanical loading events.
H Y, Stevens, D R, Meays, J A, Frangos
openaire   +2 more sources