Results 211 to 220 of about 492,458 (242)

Myosin and troponin changes in rat soleus muscle after hindlimb suspension

Journal of Applied Physiology, 1993
We examined the myosin heavy-chain (MHC), troponin T (TnT), and troponin I (TnI) isoform composition in the rat soleus muscle after 21 days of hindlimb suspension using electrophoretic and immunoblotting analysis with specific monoclonal antibodies. The suspended soleus showed a shift in the MHC isoform distribution with a marked increase (from 1.0 to
Campione M, AUSONI, SIMONETTA, Guezennec CY, SCHIAFFINO, STEFANO   +3 more
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Periodic weight support effects on rat soleus fibers after hindlimb suspension

Journal of Applied Physiology, 1988
The morphological and histochemical properties of the rat soleus were studied after 1 wk of hindlimb suspension, one model that removes the weight-bearing function of the hindlimbs. To examine the effectiveness of weight support activity in maintaining soleus mass, fiber size, and succinate dehydrogenase (SDH) activity, the hindlimbs of adult male ...
E O, Hauschka, R R, Roy, V R, Edgerton
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Adaptation of bone and tendon to prolonged hindlimb suspension in rats

Journal of Applied Physiology, 1988
The rat hindlimb suspension model was used to ascertain the importance of ground reaction forces in maintaining bone and tendon homeostasis. Young female Sprague-Dawley rats were randomly assigned to either a suspended or a nonsuspended group. After 28 days, femur bones and patellar tendons were obtained for morphological and biochemical analyses ...
A C, Vailas, D M, Deluna, L L, Lewis, S L, Curwin, R R, Roy, E K, Alford   +5 more
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Effect of anabolic steroids on skeletal muscle mass during hindlimb suspension

Journal of Applied Physiology, 1987
The efficacy of anabolic steroid treatment [0.3 or 0.9 mg nandrolone decanoate (Deca-Durabolin) per day] was examined in the context of sparing rodent fast-twitch plantaris and slow-twitch soleus muscle weight, sparing subcellular protein, and altering isomyosin expression in response to hindlimb suspension. Female rats were assigned to four groups (7
R W, Tsika, R E, Herrick, K M, Baldwin
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Structural and functional responses to prolonged hindlimb suspension in rat muscle

Journal of Applied Physiology, 1987
The purpose of this study was to investigate alterations in structural and functional properties in the soleus (SOL) and extensor digitorum longus (EDL) muscles of rats after 1, 2, and 5 wk of tail suspension. Maximal O2 uptake was 19% lower after 5 wk suspension. Loss of muscle mass was greater in SOL (63%) than in EDL (22%) muscle.
D, Desplanches, M H, Mayet, B, Sempore, R, Flandrois   +3 more
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Interaction of compensatory overload and hindlimb suspension on myosin isoform expression

Journal of Applied Physiology, 1987
The purpose of this study was to investigate the role of chronic weight-bearing activity as the primary inducer of compensatory muscle growth and changes in myosin isoform expression in rodent fast-twitch plantaris muscle. Thus, female rats were subjected to the independent and simultaneous exposure of functional overload (induced via synergist ...
R W, Tsika, R E, Herrick, K M, Baldwin
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Changes in stiffness induced by hindlimb suspension in rat Achilles tendon

European Journal of Applied Physiology, 2000
The aim of this study was to measure the effects of hindlimb suspension on mechanical properties of the rat Achilles tendon. Adult male Wistar rats were randomly assigned to groups to be either suspended, or a control. After 21 days, Achilles tendons were removed for mechanical analysis.
M I, Almeida-Silveira, D, Lambertz, C, Pérot, F, Goubel   +3 more
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Rat hindlimb muscle responses to suspension hypokinesia/hypodynamia.

Aviation, space, and environmental medicine, 1984
Hypokinetic/hypodynamic (H/H) whole body suspension of rats eliminates hindlimb load bearing functions while permitting continued use of the forelimbs. Responses of hindlimb muscles were assessed in terms of absolute and relative weights during 1 and 2 weeks of H/H suspension.
X J, Musacchia, J M, Steffen, D R, Deavers   +2 more
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Restraint vs. hindlimb suspension on fluid and electrolyte balance in rats

Journal of Applied Physiology, 1996
To determine the effect of hindlimb suspension on body fluid volume, salt and water balance, and relevant hormones, two series of experiments were performed in an experimental protocol including periods of isolation (7 days), horizontal attachment (7 days), and suspension (14 days).
F, Bouzeghrane, S, Fagette, L, Somody, A M, Allevard, C, Gharib, G, Gauquelin   +5 more
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Development of rat muscle during short- and long-term hindlimb suspension

Journal of Applied Physiology, 1987
Histochemical and contractile properties of developing rat soleus (Sol) and plantaris (P) muscles were studied after hindlimb suspension to determine the effects of reduced activity levels on muscle development. Suspension (S) began at age 18 days and lasted for 14, 28, and 206 days, and results were compared with age-matched controls.
G C, Elder, A J, McComas
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