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Reflex and muscular adaptations in rat soleus muscle after hindlimb suspension
Journal of Experimental Biology, 1999ABSTRACT Reflex, mechanical and histochemical adaptations of the soleus muscle following 3 weeks of hindlimb suspension (HS) were measured in the rat. HS transformed the soleus muscle fibre type composition from predominantly slow, type I, to approximately equal proportions of fast, type II and slow fibres.
J, Anderson +2 more
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Acupuncture ameliorated skeletal muscle atrophy induced by hindlimb suspension in mice
Biochemical and Biophysical Research Communications, 2011Preventing skeletal muscle atrophy is critical for maintaining quality of life, but it is often a challenging goal for the elderly and patients with severe conditions. We hypothesized that acupuncture in place of exercise training is an alternative non-pharmacological intervention that can help to prevent muscle atrophy.
Akiko, Onda +6 more
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Changes in fiber composition of soleus muscle during rat hindlimb suspension
Journal of Applied Physiology, 1988Chronic reduction of gravitational load in the rear limbs of rats to simulate the influence of near-zero gravity in skeletal muscles has been shown previously to elicit atrophy in the soleus muscle. Use of this model by the present investigation indicates that soleus atrophy was characterized by a decline in the number of fibers in groups that ...
G H, Templeton +4 more
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Myosin heavy chain composition of regenerated soleus muscles during hindlimb suspension
Acta Physiologica Scandinavica, 1997The aim of this study was to determine the MHC profile of regenerated soleus muscles in control (C, n = 8) and hindlimb suspended rats (HS, n = 8). After muscle degeneration was induced by injection of snake venom containing notexin, male rats were either tail suspended for 21 days or submitted to normal weight‐bearing activity.
A X, Bigard +5 more
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A Surgical Approach to Hindlimb Suspension: A Mouse Model of Disuse-Induced Atrophy.
Methods in molecular biology, 2023L. Kutz, T. Zhou, Qi Chen, Hua Zhu
semanticscholar +1 more source
Muscle mitochondrial changes by experimental immobility and hindlimb suspension.
Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology, 2003It is one of the key themata to investigate the circulatory, muscular, nervous and nutritional systems when humans stay for long time in the space environment in order to improve the safety and efficiency in manned space flight. It is well known that immobility and microgravity [correction of microgravidity] induce selective skeletal muscle atrophy ...
Y I, Goto +3 more
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Whole body and muscle respiratory capacity with dobutamine and hindlimb suspension
Journal of Applied Physiology, 1991The effects of repeated injections of dobutamine, a synthetic catecholamine, were studied in control and tail-suspended rats to determine whether this drug could improve the metabolic response to unweighting. Dobutamine prevented the decrease in maximal oxygen uptake (VO2max) induced by hindlimb suspension.
D, Desplanches +3 more
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