Results 71 to 80 of about 1,272,785 (288)

Bone Radiomics Score Derived From DXA Hip Images Enhances Hip Fracture Prediction in Older Women

, 2021
Dual-energy X-ray absorptiometry (DXA)-based bone mineral density testing is standard to diagnose osteoporosis to detect individuals at high risk of fracture.
김창오, 김현창, 김휘영, 최진영, 이유미, 홍남기   +5 more
core   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Probabilistic finite element analysis of the uncemented total hip replacement

, 2009
There are many interacting factors affecting the performance of a total hip replacement(THR), such as prosthesis design and material properties, applied loads, surgical approach, femur size and quality, interface conditions etc.
Dopico Gonzalez, Carolina
core   +1 more source

Copy number variation in CNP267 region may be associated with hip bone size. [PDF]

PLoS ONE, 2011
Osteoporotic hip fracture (HF) is a serious global public health problem associated with high morbidity and mortality. Hip bone size (BS) has been identified as one of key measurable risk factors for HF, independent of bone mineral density (BMD).
Shan-Lin Liu, Shu-Feng Lei, Fang Yang, Xi Li, Rong Liu, Shan Nie, Xiao-Gang Liu, Tie-Lin Yang, Yan Guo, Fei-Yan Deng, Qing Tian, Jian Li, Yao-Zhong Liu, Yong-Jun Liu, Hui Shen, Hong-Wen Deng   +15 more
doaj   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Tribocorrosion of total hip replacements [PDF]

, 2012
The performance of metal-on-metal total hip replacements is largely determined by their propensity to degrade in vivo. Degradation occurs through the complex interactions between wear and corrosion (termed tribocorrosion) and leads to the production of ...
Hesketh, James Edward Tilston
core   +4 more sources

Arthroscopy-assisted treatment of giant cell tumor of the proximal femur: a case report

Frontiers in Surgery
Giant cell tumor of bone (GCT) is a borderline primary bone tumor characterized by locally aggressive behavior, for which surgical management is the mainstay of treatment. Reports on GCT involving the proximal femur remain relatively limited.
Hao Chen, Ya Sun, Fei Gao, Bo Wang, Weiwei Hua   +4 more
doaj   +1 more source

Total hip arthroplasty after rotational acetabular osteotomy for developmental dysplasia of the hip: a retrospective observational study

BMC Musculoskeletal Disorders, 2022
Background Total hip arthroplasty after osteotomy is more technically challenging than primary total hip arthroplasty, especially concerning cup placement.
Takahiro Negayama, Ken Iwata, Masashi Shimamura, Teppei Senda, Tasuku Mashiba, Yoshio Kaji, Tetsuji Yamamoto   +6 more
doaj   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Reproduction of fretting wear at the stem—cement interface in total hip replacement [PDF]

, 2007
The stem-cement interface experiences fretting wear in vivo due to low-amplitude oscillatory micromotion under physiological loading, as a consequence it is considered to play an important part in the overall wear of cemented total hip replacement ...
Barrans, Simon, Barrans, S., Blunt, Liam, Zhang, H., Brown, L., Brown, Leigh, Blunt, L.   +6 more
core   +1 more source