Results 61 to 70 of about 69,756 (310)

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

The use of dual mobility acetabular cups in total hip replacement reduces dislocation rates in hip dysplasia patients

Scientific Reports, 2023
Total hip replacement arthroplasty (THA) in hip dysplasia patients has a higher dislocation rate than in patients with simple hip osteoarthritis due to anatomical deformation.
Jung Shin Kim, Nam Hoon Moon, Min Uk Do, Sung Won Jung, Kuen Tak Suh, Won Chul Shin   +5 more
doaj   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang, Rong Ren, Zhan Su, Jiahao Zhou, Pinyin Cao, Sicheng Zhang, Zhen Li, Chao Li, Songsong Zhu   +8 more
wiley   +1 more source

X-ray, anatomical and biomechanical features in patients with developmental hip dislocation [PDF]

Саратовский научно-медицинский журнал, 2014
The Pupose: to analyze X-ray, anatomical and biomechanical features in patients with developmental hip dislocation. Material and Methods. The study included 73 patients (57 women and 16 men) with the developmental hip dislocation at the age of 31 to 76 ...
Yusupov K.S., Anisimova Е.А., Pavlenko N.N., Letov A.S., Zaychev V.A., Emkyzhev O.L., Zotkin V.V., Markov D.A.   +7 more
doaj  

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Deformation‐Induced Formation of Stray Grains in Additive Manufacturing of Single Crystals

Advanced Science, EarlyView.
Stray grain formation severely limits the additive manufacturing of single‐crystal alloys. By integrating in situ synchrotron techniques, ex situ characterization, and multi‐scale multi‐physics modeling, the authors reveal that stray grains originate from dislocations at the solid‐liquid interface, rather than thermal supercooling in conventional ...
Dongsheng Zhang, Zixu Guo, Yuxiao Li, Lu Wang, Yu Wu, Darui Sun, Wentao Yan, Yuanyuan Guo, Han Wang, Wei Liu, Ye Tao, Bingbing Zhang   +11 more
wiley   +1 more source

Case Report: Traumatic obturator hip dislocation with subtrochanteric fracture in an 8-year-old child

Frontiers in Surgery
BackgroundObturator-type hip dislocation is a rare condition in pediatric patients, with the simultaneous occurrence of an ipsilateral subtrochanteric femoral fracture being exceptionally uncommon.
Shuming Huang, Kanghao Fang, Hailin Xing, Shuhua Lan, Quanzhou Wu   +4 more
doaj   +1 more source

Are Hip Precautions Necessary Post Total Hip Arthroplasty? A Systematic Review

Geriatric Orthopaedic Surgery & Rehabilitation, 2015
Purpose: Total hip arthroplasty (THA) is a common and effective treatment of hip osteoarthritis. Activity restrictions known as hip precautions are widely practiced in rehabilitation post THA, aiming to foster healing and prevent hip dislocation.
Lara Barnsley BApSci (Occupational Therapy) Hons, BMBS, Leslie Barnsley BMed (hons), Grad Clin Epi, PhD, FRACP, FAFRM (RACP), Richard Page BmedSci, MBBS, FRACS, FAOrthA   +2 more
doaj   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Surgical versus non-surgical interventions for treating patellar dislocation [PDF]

, 2015
Background: Patellar dislocation occurs when the patella disengages completely from the trochlear (femoral) groove. Following reduction of the dislocation, conservative (non-surgical) rehabilitation with physiotherapy may be used.
Apostolovic, Arnbjörnsson, Atkin, Baier, Beasley, Bennell, Bitar, Boden, Buchner, Camanho, Carter, Cash, Christiansen, Colvin, Conlan, Cosgarea, Crossley, Dath, Dejour, Donell, Donell, Fithian, Flandry, Frosch, Fukushima, Guhan, Hautamaa, Hawkins, Hing, Hing, Hsiao, Kiviluoto, Kujala, Lysholm, Marcacci, Mears, Merchant, Nietosvaara, Nietosvaara, Nikku, Nikku, Nikku, Palmu, Palmu, Paxton, Petri, Pieler-Bruha, Savarese, Scher, Schulz, Sillanpää, Sillanpää, Sillanpää, Sillanpää, Smith, Smith, Smith, Smith, Song, Stefancin, Strugnell, Tegner, Tsai, Ware, Woo   +64 more
core   +1 more source