Results 71 to 80 of about 379,693 (306)

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Surgical Hip Dislocation for Exposure of the Posterior Column. [PDF]

, 2019
Background Surgical hip dislocation is performed for safe and efficient management of acetabular fractures predominantly involving the posterior column.
Marius J.B. Keel, Keel, Marius, Johannes D. Bastian, Tannast, Moritz, Bastian, Johannes, Siebenrock, Klaus-Arno, Klaus-Arno Siebenrock, Moritz Tannast   +7 more
core   +1 more source

The use of dual mobility acetabular cups in total hip replacement reduces dislocation rates in hip dysplasia patients

Scientific Reports, 2023
Total hip replacement arthroplasty (THA) in hip dysplasia patients has a higher dislocation rate than in patients with simple hip osteoarthritis due to anatomical deformation.
Jung Shin Kim, Nam Hoon Moon, Min Uk Do, Sung Won Jung, Kuen Tak Suh, Won Chul Shin   +5 more
doaj   +1 more source

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

Advanced Science, EarlyView.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang, Yaozhi He, Yanjiao Wang, Jingjing Zhang, Qishun Liang, Mengxian Jia, Yumin Wu, Zongjie Yuan, Ziwei Fan, Yuxuan Li, Huihui Zhang, Qinjiao Fu, Ying Wang, Zhihui Huang, Honglin Teng   +14 more
wiley   +1 more source

[Operative treatment of T-type fractures of the acetabulum via surgical hip dislocation or Stoppa approach] [PDF]

, 2009
OBJECTIVE: Anatomic reduction and stable fixation by means of tissue- preserving surgical approaches. INDICATIONS Displaced acetabular fractures. Surgical hip dislocation approach with larger displacement of the posterior column in comparison to the ...
Siebenrock, KA, Tannast, M
core   +2 more sources

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Surgical hip dislocation for osteochondral transplantation as a salvage procedure for a femoral head impaction fracture.

, 2010
Obturator anterior hip dislocation is very rare. Poor results are described in patients with additional large transchondral fractures and treatment of these injuries remains challenging. Appropriate treatment recommendations are missing in the literature.
Siebenrock, KA, Büchler, L, Johannes Dominik Bastian, Baptist Keel, M J, Lorenz Büchler, Dominik Christoph Meyer, Meyer, DC, Bastian, Johannes D., Bastian, J D, Siebenrock, K A, Klaus Arno Siebenrock, Meyer, D C, Keel, MJ, Marius Johann Baptist Keel   +13 more
core   +1 more source

Changes in the spino-pelvic balance after hip replacement in patients with congenital hip dislocation

Хирургия позвоночника, 2018
Objective. To analyze the features of the sagittal spino-pelvic balance formation in patients with congenital hip dislocation and its changes after total hip replacement with restoration of the rotation center. Material and Methods.
Lev S. Shnaider, Vitaly V. Pavlov, Aleksandr V. Krutko, Vyacheslav A. Bazlov, Tariel Z. Mamuladze, Aleksey V. Peleganchuk   +5 more
doaj  

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

Advanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu, Shanyao Liu, Haixin Liang, Jiani Yang, Yanhe Li, Jiqing Yin, Xueguang Zhang, Yan Zhang, Dandan Bai, Zihui Yan, Zhuoao Zhang, Yanping Jia, Kuisheng Liu, Yifan Sheng, Jiani Xiang, Chenxiang Xi, Baoxing Dong, Xinyi Lei, Jiayu Chen, Hong Wang, Yi Guo, Yanping Zhang, Shaorong Gao, Wenqiang Liu   +23 more
wiley   +1 more source

Are Hip Precautions Necessary Post Total Hip Arthroplasty? A Systematic Review

Geriatric Orthopaedic Surgery & Rehabilitation, 2015
Purpose: Total hip arthroplasty (THA) is a common and effective treatment of hip osteoarthritis. Activity restrictions known as hip precautions are widely practiced in rehabilitation post THA, aiming to foster healing and prevent hip dislocation.
Lara Barnsley BApSci (Occupational Therapy) Hons, BMBS, Leslie Barnsley BMed (hons), Grad Clin Epi, PhD, FRACP, FAFRM (RACP), Richard Page BmedSci, MBBS, FRACS, FAOrthA   +2 more
doaj   +1 more source