Results 111 to 120 of about 205,531 (313)

Precaution, governance and the failure of medical implants: the ASR(TM) hip in the UK

open access: yes, 2014
Hip implants have provided life-changing treatment, reducing pain and improving the mobility and independence of patients. Success has encouraged manufacturers to innovate and amend designs, engendering patient hopes in these devices.
Joyce, Thomas   +2 more
core   +1 more source

Effect of femoral neck modularity upon the prosthetic range of motion in total hip arthroplasty [PDF]

open access: yes, 2014
In total hip arthroplasty, aseptic loosening and dislocation are associated with not being able to achieve the correct prosthetic component orientation.
Griffin, Damian R.   +2 more
core   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang   +32 more
wiley   +1 more source

Effect of Leg Length Discrepancy to the Hip Function on Post Hemiarthroplasty Patients in Jember

open access: yesJournal of Agromedicine and Medical Sciences (AMS), 2017
Hip fractures in elderly patient are often treated with hemiarthroplasty. Hemiarthroplasty can cause various complications, one of which is leg legth descrepancy (LLD). The function of the hip joint is reduced due to these complications. Previous studies
Yosalfa Adhista Kurniawan   +2 more
doaj   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

open access: yesAdvanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

Joint specific power production in cycling: The effect of cadence and intensity.

open access: yesPLoS ONE, 2019
BackgroundThe effect of cadence and work rate on the joint specific power production in cycling has previously been studied, but research has primarily focused on cadences above 60 rpm, without examining the effect of low cadence on joint contribution to
Lorents Ola Aasvold   +2 more
doaj   +1 more source

Accelerated wear testing methodologies for total hip replacements.

open access: yes, 2001
PhDOver the last three decades tribological studies of polyethylene total hip replacements have been undertaken using a simplified model of normal walking.
Bowsher, John G.
core  

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang   +9 more
wiley   +1 more source

Desenvolvimento de um simulador universal para ensaio de desgaste em próteses de quadril [PDF]

open access: yes, 2011
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Mecânica.Ao longo das últimas décadas a artroplastia total do quadril com componentes fabricados em ligas metálicas apoiados sobre ...
DallaCosta, Daniela Águida Bento
core  

A Biomimetic Lubricant Captures Hyaluronic Acid In Situ to Regenerate Cartilage: From Bench to Bedside

open access: yesAdvanced Science, EarlyView.
(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin   +12 more
wiley   +1 more source

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