Lung function is related to salivary cytokines and hormones in healthy children. An exploratory cross‐sectional study [PDF]
Physiological Reports, 2023 Pulmonary mechanics has been traditionally viewed as determined by lung size and physical factors such as frictional forces and tissue viscoelastic properties, but few information exists regarding potential influences of cytokines and hormones on lung ...
Laura Gochicoa‐Rangel +8 more
doaj +3 more sources
Purinergic Signaling Pathway in Human Olfactory Neuronal Precursor Cells [PDF]
Stem Cells International, 2019 Extracellular ATP and trophic factors released by exocytosis modulate in vivo proliferation, migration, and differentiation in multipotent stem cells (MpSC); however, the purinoceptors mediating this signaling remain uncharacterized in stem cells derived
Héctor Solís-Chagoyán +10 more
doaj +3 more sources
Matrix Metalloproteinases and Stress Hormones in Lung Cancer Progression. [PDF]
J Oncol, 2022 Several matrix metalloproteinases (MMPs) and psychological stress are associated with poor cancer prognosis. The current work goal was to determine MMPs’ and stress hormones’ blood concentrations from lung adenocarcinoma (LAC) patients. Patients were divided into the following groups: tobacco smokers (TS), wood smoke‐exposed (W), passive smokers (PS ...
Gonzalez-Avila G +8 more
europepmc +2 more sources
Characterization of the Signaling Pathways Activated by KCl-Induced RTK Stimulation in Guinea Pig Airways [PDF]
BiologyWe found that, in guinea pig airway smooth muscle, the pharmacological inhibition of RTKs significantly decreased the contraction induced by 20 mM KCl. We observed that MEK pharmacological inhibitors diminished the contraction induced by 20 mM KCl, but ...
Eva Herrera-Alcibar +6 more
doaj +2 more sources
Trends (2007–2019) of major atopic diseases throughout the life span in a large Mexican population [PDF]
World Allergy Organization Journal, 2023 Background: Major atopic diseases such as atopic dermatitis (AD), allergic rhinitis (AR), and asthma share the same atopic background, but they often show differences in their epidemiological behavior.
Martín Becerril-Ángeles, M.D. +3 more
doaj +2 more sources
Glycine by enteral route does not improve major clinical outcomes in severe COVID-19: a randomized clinical pilot trial [PDF]
Scientific ReportsThere is a worrying scarcity of drug options for patients with severe COVID-19. Glycine possesses anti-inflammatory, cytoprotective, endothelium-protective, and platelet-antiaggregant properties, so its use in these patients seems promising. In this open
Mario H. Vargas +7 more
doaj +2 more sources
Journal of Immunology Research, 2014 The transforming growth factor-β (TGF-β) superfamily is a family of structurally related proteins that includes TGF-β, activins/inhibins, and bone morphogenic proteins (BMPs).
Belen Tirado-Rodriguez +3 more
doaj +2 more sources
Hypoxia Induces Alterations in the Circadian Rhythm in Patients with Chronic Respiratory Diseases [PDF]
Cells, 2023 The function of the circadian cycle is to determine the natural 24 h biological rhythm, which includes physiological, metabolic, and hormonal changes that occur daily in the body.
Manuel Castillejos-López +17 more
doaj +2 more sources
International Journal of Endocrinology, 2016 The role of sex hormones in lung is known. The three main sex steroid receptors, estrogen, progesterone, and androgen, have not been sufficiently studied in airway smooth muscle cells (ASMC), and the sex hormone regulation on these receptors is unknown ...
Abraham Zarazúa +5 more
doaj +2 more sources
Functional Repercussions of Hypoxia-Inducible Factor-2α in Idiopathic Pulmonary Fibrosis [PDF]
Cells, 2022 Hypoxia and hypoxia-inducible factors (HIFs) are essential in regulating several cellular processes, such as survival, differentiation, and the cell cycle; this adaptation is orchestrated in a complex way.
Ana Karen Torres-Soria +14 more
doaj +2 more sources