Results 41 to 50 of about 19,727 (168)

Lercanidipine in general practice settings: safety and effectiveness. The LAPSE Study results

Кардиоваскулярная терапия и профилактика, 2010
Objective: To determine the safety and effectiveness of a calcium antagonist (CA) lercanidipine in the general practice settings. Material and methods: 110 patients with essential arterial hypertension (AH) were included in the study (mean age 62,3±10,8 ...
N. R. Robles, J. A. Canelada, M. Iglesias, E. Angulo, A. López Acedo, E. Díaz Olea, F. Cidoncha, M. Guerras, J. Fuentes, J. Garrido, J. Lapie, J. Peña, A. Aguilar, P. Hidalgo   +13 more
doaj  

Identification and study of new NF‐κB‐inducing kinase ligands derived from the imidazolone scaffold

Archiv der Pharmazie, Volume 358, Issue 1, January 2025.
A new family of NF‐κB‐inducing kinase (NIK) ligands bearing an imidazolone moiety were synthesized. The best compound showed a dose‐dependent inhibition of p100 to p50 processing in cellular assays, a key step in nuclear factor κB (NF‐κB) activation. Based on computational techniques, a plausible binding mode is proposed.
Francisco Maqueda‐Zelaya, Lara Valiño‐Rivas, Ana Milián, Sara Gutiérrez, José Luis Aceña, Javier Garcia‐Marin, Mª Dolores Sánchez‐Niño, Juan J. Vaquero, Alberto Ortiz   +8 more
wiley   +1 more source

Cardiopulmonary Exercise Testing With Simultaneous Echocardiography After Pulmonary Embolism

Pulmonary Circulation, Volume 15, Issue 1, January 2025.
ABSTRACT Although current guidelines recommend standard cardiopulmonary exercise testing (CPET) to evaluate symptomatic patients after pulmonary embolism (PE), CPET with simultaneous echocardiography could provide relevant information to evaluate right ventricular–pulmonary arterial coupling.
Karys Khilzi, Lucilla Piccari, Gerard Franco, Anna Rodó‐Pin, Anna Herranz, Isabel Blanco, Giuseppe Paciocco, Lorenzo Volpiano, Jose Gonzalez Garcia, Ana Diez‐Llaneza, Lluis Molina, Diego A. Rodríguez Chiaradía   +11 more
wiley   +1 more source

Association of Total Mortality and Cardiovascular Endpoints With the Timing of the First and Second Systolic Peak of the Aortic Pulse Wave

The Journal of Clinical Hypertension, Volume 27, Issue 1, January 2025.
ABSTRACT Prognostic significance of the timing in the cardiac cycle of the first (TP1) and second (TP2) systolic peak of the central aortic pulse wave is ill‐defined. Incidence rates and standardized multivariable‐adjusted hazard ratios (HRs) of adverse health outcomes associated with TP1 and TP2, estimated by the SphygmoCor software, were assessed in ...
Yi‐Bang Cheng, De‐Wei An, Lucas S. Aparicio, Qi‐Fang Huang, Yu‐Ling Yu, Chang‐Sheng Sheng, Teemu J. Niiranen, Fang‐Fei Wei, José Boggia, Katarzyna Stolarz‐Skrzypek, Natasza Gilis‐Malinowska, Valérie Tikhonoff, Wiktoria Wojciechowska, Edoardo Casiglia, Krzysztof Narkiewicz, Wen‐Yi Yang, Jan Filipovský, Kalina Kawecka‐Jaszcz, Ji‐Guang Wang, Tim S. Nawrot, Yan Li, Jan A. Staessen, the International Database of Central Arterial Properties for Risk Stratification (IDCARS) Investigators   +22 more
wiley   +1 more source

Microalbuminuria and cardiorenal risk: old and new evidence in different populations [version 1; peer review: 2 approved]

F1000Research, 2019
Since the association of microalbuminuria (MAU) with cardiovascular (CV) risk was described, a huge number of reports have emerged. MAU is a specific integrated marker of CV risk and targets organ damage in patients with hypertension, chronic kidney ...
Diego Francisco Márquez, Gema Ruiz-Hurtado, Julian Segura, Luis Ruilope   +3 more
doaj   +1 more source

American registry of ambulatory and acute decompensated heart failure (AMERICCAASS registry): Rationale and design

ESC Heart Failure, Volume 11, Issue 6, Page 3805-3813, December 2024.
Abstract Aims Heart failure (HF) is a highly prevalent and progressive condition associated with significant morbidity and mortality rates. Acute decompensated HF precipitates millions of hospitalizations each year. Despite therapeutic advances, the overall prognosis of HF is poor. The varying clinical courses and outcomes of patients with this disease
Juan Esteban Gómez‐Mesa, Juliana María Gutiérrez‐Posso, Manuela Escalante‐Forero, David Esteban Eraso‐Bolaños, Mark H. Drazner, Daniel Quesada‐Chaves, Alexander Romero‐Guerra, Eduardo R. Perna, Amada Álvarez‐Sangabriel, Víctor Rossel, Walter Alarco, Mario Speranza   +11 more
wiley   +1 more source

Intermanufacturer assessment of diagnostic performance of angiogenic ratio vs glycosylated fibronectin in women with suspected pre‐eclampsia

Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 5, Page 620-625, November 2024.
ABSTRACT Objective To compare the diagnostic performance of different manufacturers' immunoassays for the soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio with that of a point‐of‐care (PoC) test for glycosylated fibronectin (GlyFn) in women with suspected pre‐eclampsia (PE).
I. Y. M. Wah, D. S. Sahota, N. K. L. Wong, N. M. W. Lee, C. J. Liu, C. S. L. Lau, H. H. Y. Leung, L. C. Poon   +7 more
wiley   +1 more source

Postnatal outcome following fetal aortic valvuloplasty for critical aortic stenosis

Ultrasound in Obstetrics &Gynecology, Volume 64, Issue 3, Page 339-347, September 2024.
ABSTRACT Objective To report our experience of fetal aortic valvuloplasty (FAV) for critical aortic stenosis (AS), with a focus on the postnatal evolution of the patients. Methods This was a retrospective study including all fetuses with critical AS which underwent FAV in a single center between January 2011 and June 2022.
R. Corroenne, M. Meot, L. J. Salomon, I. Szezepanski, H. Baghdadi, B. Stos, M. Levy, J. Le Bidois, D. Laux, R. Gaudin, O. Raisky, Y. Ville, D. Bonnet, J. Stirnemann, S. Malekzadeh‐Milani   +14 more
wiley   +1 more source

Selective fetal growth restriction in dichorionic diamniotic twin pregnancy: systematic review and meta‐analysis of pregnancy and perinatal outcomes

Ultrasound in Obstetrics &Gynecology, Volume 63, Issue 2, Page 164-172, February 2024.
ABSTRACT Objective Most of the published literature on selective fetal growth restriction (sFGR) has focused on monochorionic twin pregnancies. The aim of this systematic review was to report on the outcome of dichorionic diamniotic (DCDA) twin pregnancies complicated by sFGR.
F. D'Antonio, S. Prasad, L. Masciullo, N. Eltaweel, A. Khalil   +4 more
wiley   +1 more source

Pulmonary vascular pressure respiratory swings in COPD and ILD candidates for lung transplantation: Large but different

Pulmonary Circulation, Volume 14, Issue 1, January 2024.
Abstract We analyzed the effect of respiratory swings on interpreting intravascular pulmonary vascular pressures (PVPs) in chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) candidates for lung transplantation (LTx) and the role of the alterations in pulmonary function tests on the dynamic respiratory variations.
Juan C. Grignola, Alvaro Calabuig, Pedro Trujillo, Carles Bravo, Fernando Azpiroz, Manuel López Messeguer, Enric Domingo   +6 more
wiley   +1 more source