Parallel and convergent processing in grid cell, head-direction cell, boundary cell, and place cell networks. [PDF]
, 2013 The brain is able to construct internal representations that correspond to external spatial coordinates. Such brain maps of the external spatial topography may support a number of cognitive functions, including navigation and memory.
Brandon, Mark P +2 more
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Hippocampal TERT Regulates Spatial Memory Formation through Modulation of Neural Development
Stem Cell Reports, 2017 Summary: The molecular mechanism of memory formation remains a mystery. Here, we show that TERT, the catalytic subunit of telomerase, gene knockout (Tert−/−) causes extremely poor ability in spatial memory formation.
Qi-Gang Zhou +17 more
doaj +1 more source
Postmortem Studies of the Hippocampal Formation in Schizophrenia [PDF]
Schizophrenia Bulletin, 1997 Many postmortem studies report differences between the hippocampal formations of patients with schizophrenia and those of controls. These differences include volume changes, cell density changes, periventricular gliosis, senile degenerative changes, and abnormalities of neuronal size, position, or orientation.
openaire +3 more sources
Journal of Neuroscience, 2011 Tropomyosin-related kinase B receptor (TrkB) is a neurotrophin receptor important for the synaptic plasticity underlying hippocampal-dependent learning and memory.
Joanna L. Spencer-Segal +5 more
semanticscholar +1 more source
Hippocampal structural plasticity accompanies the resulting contextual fear memory following stress and fear conditioning [PDF]
, 2013 The present research investigated the resulting contextual fear memory and structural plasticity changes in the dorsal hippocampus (DH) following stress and fear conditioning. This combination enhanced fear retention and increased the number of total and
Calfa, Gaston Diego +2 more
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Integrating Spatial Working Memory and Remote Memory: Interactions between the Medial Prefrontal Cortex and Hippocampus [PDF]
, 2017 In recent years, two separate research streams have focused on information sharing between the medial prefrontal cortex (mPFC) and hippocampus (HC).
Hyman, James M., Wirt, Ryan A
core +3 more sources
Properties of Contextual Memory Formed in the Absence of αCaMKII Autophosphorylation
Molecular Brain, 2011 The alpha-isoform of calcium/calmodulin-dependent kinase II (αCaMKII) is a major synaptic kinase that undergoes autophosphorylation after NMDA receptor activation, switching the kinase into a calcium-independent activity state.
Irvine Elaine E +7 more
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PharmaceuticalsTramadol and tapentadol are chemically related opioids prescribed for the analgesia of moderate to severe pain. Although safer than classical opioids, they are associated with neurotoxicity and behavioral dysfunction, which arise as a concern ...
Cristiana Soares-Cardoso +6 more
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Frontiers in Neuroscience, 2018 Propofol inhibits long-term potentiation (LTP) in the hippocampal CA1 region and impedes episodic memory formation. However, the molecular mechanisms involved in the effect of propofol are still poorly understood.
Weiwei Li +10 more
doaj +1 more source
Lesions of perirhinal and parahippocampal cortex that spare the amygdala and hippocampal formation produce severe memory impairment [PDF]
, 1989 Stuart Zola‐Morgan +3 more
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