Results 111 to 120 of about 242,255 (327)

Wnt/β-catenin signaling stimulates the expression and synaptic clustering of the autism-associated Neuroligin 3 gene [PDF]

, 2018
Indexación: Scopus.Synaptic abnormalities have been described in individuals with autism spectrum disorders (ASD). The cell-adhesion molecule Neuroligin-3 (Nlgn3) has an essential role in the function and maturation of synapses and NLGN3 ASD-associated ...
Andrade, V.M., Avila, M.E., Caracci, M.O., De Ferrari, G.V., Medina, M.A., Opazo, C., Reyes, A.E., Ugarte, G.D., Vargas, M.F., Verdugo, D.A.   +9 more
core   +1 more source

Implantable Nongenetic Optoelectronic Biointerfaces for Neuromodulation

Advanced Photonics Research, EarlyView.
This review summarizes recent advances in semiconductor‐based optoelectronic biointerfaces for wireless, optically induced electrical neuromodulation. It highlights their diverse designs that enable precise, targeted neural modulation of cells, tissues, and organs.
Jinglin Ye, Jinwei Huang, Wenyu Nie, Jianming Xu, Xing Sheng, Huachun Wang   +5 more
wiley   +1 more source

Hippocampal TERT Regulates Spatial Memory Formation through Modulation of Neural Development

Stem Cell Reports, 2017
Summary: The molecular mechanism of memory formation remains a mystery. Here, we show that TERT, the catalytic subunit of telomerase, gene knockout (Tert−/−) causes extremely poor ability in spatial memory formation.
Qi-Gang Zhou, Meng-Ying Liu, Han-Woong Lee, Fuyuki Ishikawa, Sushil Devkota, Xin-Ru Shen, Xin Jin, Hai-Yin Wu, Zhigang Liu, Xiao Liu, Xun Jin, Hai-Hui Zhou, Eun Jeoung Ro, Jing Zhang, Yu Zhang, Yu-Hui Lin, Hoonkyo Suh, Dong-Ya Zhu   +17 more
doaj   +1 more source

Working memory learning method and astrocytes number in different subfields of rat's Hippocampus [PDF]

, 2008
The aim of this study was evaluation of the astrocytes number in different subfields of rat's Hippocampus after spatial learning with usage of Morris Water Maze technique and working memory method.
Abbas, P., Ahmad, H., Mehrdad, J., Naser, N., Yousef, S.   +4 more
core   +1 more source

Postmortem Studies of the Hippocampal Formation in Schizophrenia [PDF]

Schizophrenia Bulletin, 1997
Many postmortem studies report differences between the hippocampal formations of patients with schizophrenia and those of controls. These differences include volume changes, cell density changes, periventricular gliosis, senile degenerative changes, and abnormalities of neuronal size, position, or orientation.
openaire   +3 more sources

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Radiation-induced lowered neurogenesis associated with shortened latency of inhibitory avoidance memory response [PDF]

, 2011
The neural system is less sensitive to radiation than other late-responding organs and tissues such as the kidney and lung. The generation of new neurons in the adult mammalian brain has been documented in several works.
Azami, N.S., Heidari, M., Jahanshahi, M., Khoshnazar, A.K.   +3 more
core  

Hippocampus-dependent emergence of spatial sequence coding in retrosplenial cortex. [PDF]

, 2018
Retrosplenial cortex (RSC) is involved in visuospatial integration and spatial learning, and RSC neurons exhibit discrete, place cell-like sequential activity that resembles the population code of space in hippocampus.
Bonin, Vincent, Mao, Dun, McNaughton, Bruce L, Mohajerani, Majid H, Neumann, Adam R, Sun, Jianjun   +5 more
core   +2 more sources

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

Advanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong, Lin‐Lin Hu, Ling Jiang, Pei‐Xia Shi, Shuang Zhang, Yuan Zhao, Bing‐Qiao Wang, Xiao‐Feng Cheng, Cheng‐Kang He, Sen Lin, Yue Dai, Zhao‐You Meng, Chen‐Hao Zhao, Bao‐Liang Sun, Qi Xie, Fang‐Fei Li, Qing‐Wu Yang   +16 more
wiley   +1 more source

Human iPSC‐Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease

Advanced Science, EarlyView.
Short‐term intravenous treatments with iPSC‐derived mononuclear phagocytes (iMPs) improve cognitive decline and neural health in two mouse models of aging and in the 5xFAD mouse model of Alzheimer's disease. iMPs reduce levels of serum amyloid proteins that increase in aging and improve the health of hippocampal microglia and mossy cells.
V. Alexandra Moser, Luz Jovita Dimas‐Harms, Rachel M. Lipman, Jake Inzalaco, Shaughn Bell, Michelle Alcantara, Erikha Valenzuela, George Lawless, Simion Kreimer, Sarah J. Parker, Helen S. Goodridge, Clive N. Svendsen   +11 more
wiley   +1 more source