Results 141 to 150 of about 4,772,903 (306)

Mammalian Tolerance to Amino Acid Heterochirality

open access: yesChemBioChem, Accepted Article.
Organisms use amino acids predominantly in l‐configuration. On the other hand, a series of studies show that a variety of d‐amino acids also occur in mammals and amino acid homochirality is not complete. Mammals de novo synthesize most amino acids with l‐configuration, but serine and aspartate are converted from l‐ to d‐configuration by endogenous ...
Jumpei Sasabe   +4 more
wiley   +1 more source

Hippocampal TERT Regulates Spatial Memory Formation through Modulation of Neural Development

open access: yesStem Cell Reports, 2017
Summary: The molecular mechanism of memory formation remains a mystery. Here, we show that TERT, the catalytic subunit of telomerase, gene knockout (Tert−/−) causes extremely poor ability in spatial memory formation.
Qi-Gang Zhou   +17 more
doaj  

Basal forebrain cholinergic cell attachment and neurite outgrowth on organotypic slice cultures of hippocampal formation [PDF]

open access: green, 2002
Elena Tsai   +5 more
openalex   +1 more source

Affinity‐Based Protein Profiling Reveals IDH2 as a Mitochondrial Target of Cannabinol in Receptor‐Independent Neuroprotection

open access: yesChemistry – A European Journal, EarlyView.
A chemical probe CBN‐P based on the neuroprotective cannabinoid cannabinol (CBN) was developed and synthesized. CNB‐P was found to have a similar mechanism of action as the parent compound and was used in click‐CLEM microscopy studies and affinity‐based protein profiling to identify the mitochondrial protein isocitrate dehydrogenase 2 (IDH2) as one ...
Eva Schaller   +5 more
wiley   +1 more source

Space in the brain: how the hippocampal formation supports spatial cognition

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2014
T. Hartley   +3 more
semanticscholar   +1 more source

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