Results 11 to 20 of about 249,413 (328)

Hippocampal subregion abnormalities in schizophrenia: A systematic review of structural and physiological imaging studies [PDF]

open access: yesNeuropsychopharmacology Reports, 2018
Aim The hippocampus is considered a key region in schizophrenia pathophysiology, but the nature of hippocampal subregion abnormalities and how they contribute to disease expression remain to be fully determined.
Soichiro Nakahara   +2 more
doaj   +2 more sources

Hippocampal Global Remapping Can Occur without Input from the Medial Entorhinal Cortex. [PDF]

open access: yes, 2018
The high storage capacity of the episodic memory system relies on distinct representations for events that are separated in time and space. The spatial component of these computations includes the formation of independent maps by hippocampal place cells ...
Boublil, Brittney L   +4 more
core   +5 more sources

Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2. [PDF]

open access: yes, 2012
BACKGROUND: It is becoming increasingly evident that deficits in the cortex and hippocampus at early stages of dementia in Alzheimer's disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-β peptide (Aβ42).
Alifragis, P   +5 more
core   +9 more sources

Structural organization of the rat hyppocampal formation

open access: yesСибирский научный медицинский журнал, 2023
The review examines the historical aspects of the hippocampus nomenclature. Its anatomical study began by the ancient Greeks, who called the unusual–looking structure a “ram’s horn” – cornu ammonis. The term “hippocampus” (ancient Greek: ἱππόκαμπος, from
S. M. Zimatkin   +2 more
doaj   +1 more source

Chronic Stress Alters Behavior in the Forced Swim Test and Underlying Neural Activity in Animals Exposed to Alcohol Prenatally: Sex- and Time-Dependent Effects

open access: yesFrontiers in Behavioral Neuroscience, 2018
Dysregulation of the hypothalamic-pituitary-adrenal (HPA) stress response has been suggested to play a role in vulnerability to stress-related disorders, such as depression.
Vivian Y. Y. Lam   +6 more
doaj   +1 more source

Corticosteroids: Sculptors of the Hippocampal Formation [PDF]

open access: yesReviews in the Neurosciences, 2002
The influence of corticosteroids on hippocampus-dependent learning and memory processes is now indisputable. On the other hand, closer scrutiny of early studies together with interpretations from newer studies would suggest that the proposition that corticosteroid-induced hippocampal cell death accounts fully for the associated cognitive deficits is ...
Sousa, Nuno, Almeida, O. F. X.
openaire   +4 more sources

Effect of scopolamine-based amnesia on the number of astrocytes in the rat's hippocampus [PDF]

open access: yes, 2012
As neuron-astrocyte interactions play a crucial role in the adult brain, it is thought that astrocytes support learning and memory through specific mechanisms.
Azami, N.S.   +2 more
core   +1 more source

Fan cells in lateral entorhinal cortex directly influence medial entorhinal cortex through synaptic connections in layer 1

open access: yeseLife, 2022
Standard models for spatial and episodic memory suggest that the lateral entorhinal cortex (LEC) and medial entorhinal cortex (MEC) send parallel independent inputs to the hippocampus, each carrying different types of information.
Brianna Vandrey   +4 more
doaj   +1 more source

Hippocampal formation-inspired probabilistic generative model

open access: yesNeural Networks, 2022
In building artificial intelligence (AI) agents, referring to how brains function in real environments can accelerate development by reducing the design space. In this study, we propose a probabilistic generative model (PGM) for navigation in uncertain environments by integrating the neuroscientific knowledge of hippocampal formation (HF) and the ...
Akira Taniguchi   +2 more
openaire   +3 more sources

Spatial goal coding in the hippocampal formation [PDF]

open access: yesNeuron, 2022
The mammalian hippocampal formation contains several distinct populations of neurons involved in representing self-position and orientation. These neurons, which include place, grid, head direction, and boundary cells, are thought to collectively instantiate cognitive maps supporting flexible navigation.
Nyberg, Nils   +3 more
openaire   +3 more sources

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