Results 221 to 230 of about 249,413 (328)

Faculty Opinions recommendation of Hippocampal 5-HT Input Regulates Memory Formation and Schaffer Collateral Excitation.

, 2018
Sreedharan Sajikumar, Amrita Benoy
openalex   +2 more sources

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu, Zhiyang Zeng, Xinyu Ming, Shuming Yin, Yuting Guan, Liangcai Gao, Dali Li   +6 more
wiley   +1 more source

Comparison of surgical approaches to the hippocampal formation with artificial intelligence. [PDF]

Neurosurg Rev
Dundar TT, Pehlivanoğlu MK, Eker AG, Albayrak NB, Mutluer AS, Yurtsever İ, Doğan İ, Duru N, Türe U.   +8 more
europepmc   +1 more source

Intraneuronal sortilin aggregation relative to granulovacuolar degeneration, tau pathogenesis and sorfra plaque formation in human hippocampal formation. [PDF]

Front Aging Neurosci, 2022
Jiang J, Yang C, Ai JQ, Zhang QL, Cai XL, Tu T, Wan L, Wang XS, Wang H, Pan A, Manavis J, Gai WP, Che C, Tu E, Wang XP, Li ZY, Yan XX.   +16 more
europepmc   +1 more source

Hub genes and diagnostic model associated with mitochondrial function in Alzheimer's disease

Animal Models and Experimental Medicine, EarlyView.
Alzheimer's disease (AD) is the most common neurodegenerative disorder, and mitochondrial dysfunction has been confirmed in AD patients and mouse models. However, the pathogenic genes associated with AD and early diagnostic methods based on mitochondrial function remain to be explored.
Xuchao Zhu, Ling Zhang, Chuan Qin
wiley   +1 more source

Parvalbumin interneurons in the hippocampal formation of individuals with Alzheimer's disease: a neuropathological study of abnormal phosphorylated tau in neurons. [PDF]

Front Neuroanat
Merino-Serrais P, Plaza-Alonso S, Tapia-Gonzalez S, León-Espinosa G, DeFelipe J.   +4 more
europepmc   +1 more source

Association of Tau Pathology With Clinical Symptoms in the Subfields of Hippocampal Formation. [PDF]

Front Aging Neurosci, 2021
Ge X, Zhang D, Qiao Y, Zhang J, Xu J, Zheng Y.   +5 more
europepmc   +1 more source

Comparative Study of ROCK1 and ROCK2 in Hippocampal Spine Formation and Synaptic Function

, 2019
Jinglan Yan, Youcan Pan, Xiaoyan Zheng, Chuanan Zhu, Yu Zhang, Guoqi Shi, Lin Yao, Yongjun Chen, Nenggui Xu   +8 more
openalex   +2 more sources

Polyphenol diet and exercise as neuroprotective factors in a Drosophila model of Alzheimer's disease

Animal Models and Experimental Medicine, EarlyView.
Moderate exercise and low‐dose ellagic acid supplementation improved motor performance, learning, and longevity in a transgenic Drosophila model of Alzheimer's disease. Both interventions showed hormetic effects—that is, beneficial at low levels, but detrimental at higher intensities or doses.
Michelle Morgan, Zaida Lopez Rodriguez, Richard E. Hartman   +2 more
wiley   +1 more source

Sequence and trajectory of early Alzheimer's disease-related tau inclusions in the hippocampal formation of cases without amyloid-β deposits. [PDF]

Acta Neuropathol
Braak H, Mayer B, Feldengut S, Schön M, Del Tredici K.   +4 more
europepmc   +1 more source