Results 261 to 270 of about 4,772,903 (306)
We introduced the basic characterization and isolation methods of PEVs, reviewed the PEVs‐related articles pertaining to disease therapy and drug delivery system, and summarized the drug loading methods, storage techniques, and engineering modification strategies of the carrier, to establish a safer, more efficient and more affordable approach for ...
Jichun Yang+14 more
wiley +1 more source
Mitochondrial dysfunction: Related diseases, influencing factors, and detection
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li+9 more
wiley +1 more source
Sensing Dog Brain Reactions to Smell by AI Speckle Pattern Analysis
The setup of our experiment is shown on Labrador, Johny, a canine participant of our research. The schematic of the setup features: green laser, digital camera, source of smell, and computer. Regions of the brain that were tested are highlighted. Note that the hippocampus and amygdala are on both sides of the dog's brain.
Ilana Propp+5 more
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Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
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Abstract Childhood maltreatment is recognized as a risk factor for cognitive decline in adulthood. However, the mechanisms underlying this association, particularly the role of systemic inflammation, remain understudied. To address this gap, this study investigated the indirect effects of inflammation on the associations between childhood maltreatment ...
Dalia Einstein+3 more
wiley +1 more source
Key concepts, methods, findings, and questions about traumatic memories
Abstract This article is based on a Lifetime Achievement Award lecture delivered at the 40th Annual Meeting of the International Society for Traumatic Stress Studies in Boston (Massachusetts, United States) in September 2024. Understanding traumatic memory involves integrating clinical observations with a wide range of knowledge from philosophy ...
Chris R. Brewin
wiley +1 more source
The “Hand-as-Foot” teaching method in hippocampal formation
Yang Yu+3 more
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Alzheimer's disease: cell-specific pathology isolates the hippocampal formation.
Science, 1984Examination of temporal lobe structures from Alzheimer patients reveals a specific cellular pattern of pathology of the subiculum of the hippocampal formation and layers II and IV of the entorhinal cortex.
B. Hyman+3 more
semanticscholar +1 more source
Anatomy of the hippocampal formation.
Monographs in neural sciences, 2014The hippocampus is one of several brain regions that together comprise the hippocampal formation. The hippocampal formation is a prominent C-shaped structure bulging in the floor of the temporal horn of the lateral ventricle.
C. Schultz, M. Engelhardt
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The primate hippocampal formation: evidence for a time-limited role in memory storage.
Science, 1990Clinical and experimental studies have shown that the hippocampal formation and related structures in the medial temporal lobe are important for learning and memory.
S. Zola-Morgan, L. Squire
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