Results 271 to 280 of about 249,413 (328)
The Influence of Omega‐3 Fatty Acids and Probiotics on Hippocampal Inflammation and Glial Cells in a Chronic Anorexia Nervosa Rat Model
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective
Anorexia nervosa (AN) is a severe eating disorder associated with brain volume reduction, glial cell loss, microbiome alterations, and dysregulated pro‐inflammatory mechanisms. However, the underlying cellular mechanisms remain inadequately elucidated, and interventions addressing these alterations are lacking.A. C. Thelen, N. Andreani, N. M. Korten, M. Neumann, V. Verspohl, M. van Egmond, L. Kneisel, C. Voelz, L. Blischke, J. F. Baines, J. Baier, J. Schumacher, F. Kiessling, B. Herpertz‐Dahlmann, C. Beyer, L. Keller, J. Seitz, S. Trinh +17 morewiley +1 more sourceExploring the role of apolipoprotein ε4 in progressive myoclonic epilepsy type 1
Epileptic Disorders, EarlyView.Abstract Objective
Progressive myoclonic epilepsy type 1 (EPM1) is a neurodegenerative disease caused by biallelic variants in the cystatin B (CSTB) gene. Despite a progressive course, phenotype severity varies among patients, even within families. We studied the potential role of APOE ε4 in modifying phenotypic diversity in EPM1, given its established Janina Gunnar, Yawu Liu, Henri Eronen, Tarja Joensuu, Marja Äikiä, Jelena Hyppönen, Katri Silvennoinen, Esa Mervaala, Juhana Hakumäki, Anna‐Elina Lehesjoki, Reetta Kälviäinen +10 morewiley +1 more sourceVolumetric MRI study of the brain in patients with neurocysticercosis and mesial temporal lobe epilepsy
Epileptic Disorders, EarlyView.Abstract Objective
Neurocysticercosis (NCC) is a common parasitic infection of the central nervous system and a known cause of focal epilepsy. Its potential role in triggering or contributing to mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is suggested, but the impact on brain volumetry remains unclear.Jaisa Quedi Araújo, Bruna da Silveira Arruda, Sandra Polita, Maurício Anés, Thiago Junqueira Ribeiro de Rezende, Matheus de Lima Ruffini, Adolfo Moraes de Souza, Jordana Soares Chaves, Fabiano Reis, Marino Muxfeldt Bianchin, Juliana Ávila Duarte +10 morewiley +1 more sourceLong‐term predictors of seizure outcome after anterior temporal lobectomy in unilateral hippocampal sclerosis: A 281‐patient cohort with mean 10‐year follow‐up
Epileptic Disorders, EarlyView.Abstract Objective
To identify long‐term predictors of seizure outcome after anterior temporal lobectomy (ATL) in a large, homogeneous cohort of patients with drug‐resistant temporal lobe epilepsy (TLE) and MRI‐defined unilateral hippocampal sclerosis (HS), all operated on by a single neurosurgeon with extended follow‐up.Thiago Pereira Rodrigues, Leonardo Favi Bocca, Elza Marcia Targas Yacubian, Mirian Salvadori Bittar Guaranha, Neide Barreira Alonso, Henrique Carrete Junior, Maria Helena Silva Noffs, Luis Otavio Caboclo, Jeana Torres Corso Duarte, Ricardo Silva Centeno +9 morewiley +1 more sourceMesial temporal lobe epilepsy with hippocampal sclerosis: Seizure, neuropsychological, and quality of life outcomes of 100 patients treated with trans‐anterior T1 selective amygdalohippocampectomy
Epileptic Disorders, EarlyView.Abstract Objective
For mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE with HS), laser interstitial thermal therapy has recently been increasingly used. At our institute, however, selective amygdalohippocampectomy by a trans‐anterior T1 subpial approach (trans‐anterior T1 SAH) has been used for MTLE with HS. Here, we examined the seizure,Naotaka Usui, Hiroshi Ogawa, Akihiko Kondo, Kazumi Matsuda, Mitsuru Hashiguchi, Taro Okumura, Yuuki Ishida, Norihiko Kawaguchi, Takashi Matsudaira, Kentaro Tokumoto, Takuji Nishida, Katsumi Imai +11 morewiley +1 more sourcePseudoaneurysms as a complication of stereoelectroencephalography: Case series and clinical recommendations
Epilepsia, EarlyView.Abstract Objective
Stereoelectroencephalography (sEEG) is commonly employed in the workup for epilepsy surgery in patients with focal drug‐resistant epilepsy (DRE). Intracranial hemorrhage is a known complication, with reported incidence rates ranging from .9% to 19.1%. Rarely, pseudoaneurysms have been reported in literature as a potential cause. This Youssra El Khou, Rick H. G. J. van Lanen, G. Louis Wagner, Simon Tousseyn, Gwendolyn de Bruyn, Christianne M. C. Hoeberigs, Bart A. J. M. Wagemans, Christiaan van der Leij, Sylvia Klinkenberg, Jeske Nelissen, Pieter L. Kubben, Olaf E. M. G. Schijns, Jim T. A. Dings, Kim Rijkers, on behalf of the ACE Epilepsy Surgery group, Gwendolyn de Bruyn, Albert Colon, Jim Dings, Marc Hendriks, Danny Hilkman, Christianne Hoeberigs, Jochem van der Pol, Lotte de Jong, Kim Rijkers, Sylvia Klinkenberg, Vivianne van Kranen Mastenbroek, Jeske Nelissen, Pieter Kubben, Walter M. Palm, Rob P. W. Rouhl, Olaf Schijns, Simon Tousseyn, Marielle Vlooswijk, Louis Wagner, Dorien Weckhuysen, Ilse van Straaten +35 morewiley +1 more source