Results 21 to 30 of about 242,255 (327)

Morphological Variations of Hippocampal Formation in Epilepsy

Pediatric Neurology Briefs, 2013
Researchers at Hospital Sao Paulo and other centers in Brazil compared the hippocampal formation (HF) morphology of healthy asymptomatic individuals (n=30) with that of patients with mesial temporal lobe epilepsy and hippocampal sclerosis (MTLE-HS)(n=68),
J Gordon Millichap
doaj   +1 more source

Framing of grid cells within and beyond navigation boundaries

eLife, 2017
Grid cells represent an ideal candidate to investigate the allocentric determinants of the brain’s cognitive map. Most studies of grid cells emphasized the roles of geometric boundaries within the navigational range of the animal. Behaviors such as novel
Francesco Savelli, JD Luck, James J Knierim   +2 more
doaj   +1 more source

Electrophysiological Signatures of Spatial Boundaries in the Human Subiculum. [PDF]

, 2018
Environmental boundaries play a crucial role in spatial navigation and memory across a wide range of distantly related species. In rodents, boundary representations have been identified at the single-cell level in the subiculum and entorhinal cortex of ...
Aronson, Joshua P., Berry, Brent M., Das, Sandhitsu R., Davis, Kathryn A., Gorniak, Richard, Gross, Robert E., Jacobs, Joshua, Lee, Sang Ah, Lega, Bradley, Miller, Jonathan F., Rizzuto, Daniel S., Sharan, Ashwini, Sheth, Sameer, Sperling, Michael R., Stein, Joel M, Watrous, Andrew J., Worrell, Gregory A.   +16 more
core   +2 more sources

Chronic Stress Alters Behavior in the Forced Swim Test and Underlying Neural Activity in Animals Exposed to Alcohol Prenatally: Sex- and Time-Dependent Effects

Frontiers in Behavioral Neuroscience, 2018
Dysregulation of the hypothalamic-pituitary-adrenal (HPA) stress response has been suggested to play a role in vulnerability to stress-related disorders, such as depression.
Vivian Y. Y. Lam, Charlis Raineki, Lily E. Takeuchi, Linda Ellis, Todd S. Woodward, Todd S. Woodward, Joanne Weinberg   +6 more
doaj   +1 more source

Effect of scopolamine-based amnesia on the number of astrocytes in the rat's hippocampus [PDF]

, 2012
As neuron-astrocyte interactions play a crucial role in the adult brain, it is thought that astrocytes support learning and memory through specific mechanisms.
Azami, N.S., Jahanshahi, M., Nickmahzar, E.   +2 more
core   +1 more source

Fan cells in lateral entorhinal cortex directly influence medial entorhinal cortex through synaptic connections in layer 1

eLife, 2022
Standard models for spatial and episodic memory suggest that the lateral entorhinal cortex (LEC) and medial entorhinal cortex (MEC) send parallel independent inputs to the hippocampus, each carrying different types of information.
Brianna Vandrey, Jack Armstrong, Christina M Brown, Derek LF Garden, Matthew F Nolan   +4 more
doaj   +1 more source

Establishing the boundaries: the hippocampal contribution to imagining scenes [PDF]

, 2010
When we visualize scenes, either from our own past or invented, we impose a viewpoint for our “mind's eye” and we experience the resulting image as spatially coherent from that viewpoint.
Bird, Chris M, Burgess, Neil, Capponi, Corinne, Doeller, Christian F, King, John A   +4 more
core   +1 more source

Space and Memory (Far) Beyond the Hippocampus: Many Subcortical Structures Also Support Cognitive Mapping and Mnemonic Processing

Frontiers in Neural Circuits, 2019
Memory research remains focused on just a few brain structures—in particular, the hippocampal formation (the hippocampus and entorhinal cortex). Three key discoveries promote this continued focus: the striking demonstrations of enduring anterograde ...
Shane M. O’Mara, John P. Aggleton
doaj   +1 more source

Spatial cell firing during virtual navigation of open arenas by head-restrained mice

eLife, 2018
We present a mouse virtual reality (VR) system which restrains head-movements to horizontal rotations, compatible with multi-photon imaging. This system allows expression of the spatial navigation and neuronal firing patterns characteristic of real open ...
Guifen Chen, John Andrew King, Yi Lu, Francesca Cacucci, Neil Burgess   +4 more
doaj   +1 more source

Intermediate levels of hippocampal activity appear optimal for associative memory formation. [PDF]

PLoS ONE, 2010
BACKGROUND: It is well established that hippocampal activity is positively related to effective associative memory formation. However, in biological systems often optimal levels of activity are contrasted by both sub- and supra-optimal levels.
Xiao Liu, Shaozheng Qin, Mark Rijpkema, Jing Luo, Guillén Fernández   +4 more
doaj   +1 more source