Results 21 to 30 of about 250,571 (331)
Spatial cell firing during virtual navigation of open arenas by head-restrained mice
eLife, 2018 We present a mouse virtual reality (VR) system which restrains head-movements to horizontal rotations, compatible with multi-photon imaging. This system allows expression of the spatial navigation and neuronal firing patterns characteristic of real open ...
Guifen Chen +4 more
doaj +1 more source
Frontiers in Behavioral Neuroscience, 2018 Dysregulation of the hypothalamic-pituitary-adrenal (HPA) stress response has been suggested to play a role in vulnerability to stress-related disorders, such as depression.
Vivian Y. Y. Lam +6 more
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An automated, geometry-based method for hippocampal shape and thickness analysis [PDF]
Neuroimage 276 (2023) 120182, 2023 The hippocampus is one of the most studied neuroanatomical structures due to its involvement in attention, learning, and memory as well as its atrophy in ageing, neurological, and psychiatric diseases. Hippocampal shape changes, however, are complex and cannot be fully characterized by a single summary metric such as hippocampal volume as determined ...
arxiv +1 more source
Frontiers in Neural Circuits, 2019 Memory research remains focused on just a few brain structures—in particular, the hippocampal formation (the hippocampus and entorhinal cortex). Three key discoveries promote this continued focus: the striking demonstrations of enduring anterograde ...
Shane M. O’Mara, John P. Aggleton
doaj +1 more source
Intermediate levels of hippocampal activity appear optimal for associative memory formation. [PDF]
PLoS ONE, 2010 BACKGROUND: It is well established that hippocampal activity is positively related to effective associative memory formation. However, in biological systems often optimal levels of activity are contrasted by both sub- and supra-optimal levels.
Xiao Liu +4 more
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eLife, 2022 Standard models for spatial and episodic memory suggest that the lateral entorhinal cortex (LEC) and medial entorhinal cortex (MEC) send parallel independent inputs to the hippocampus, each carrying different types of information.
Brianna Vandrey +4 more
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Adult Hippocampal Neurogenesis: Regulation and Possible Functional and Clinical Correlates
Frontiers in Neuroanatomy, 2018 The formation of new neurons in the adult central nervous system (CNS) has been recognized as one of the major findings in neuroanatomical research. The hippocampal formation (HF), one of the main targets of these investigations, holds a neurogenic niche
Pedro Baptista +2 more
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Querying hippocampal replay with subcortical inputs [PDF]
arXiv, 2022 During sleep, the hippocampus recapitulates neuronal patterns corresponding to behavioral trajectories during previous experiences. This hippocampal replay supports the formation of long-term memories. Yet, whether replay originates within the hippocampal circuitry or is initiated by extrahippocampal inputs is unknown.
arxiv
Updating the lamellar hypothesis of hippocampal organization
Frontiers in Neural Circuits, 2012 In 1971, Andersen and colleagues proposed that excitatory activity in the entorhinal cortex propagates topographically to the dentate gyrus, and on through a trisynaptic circuit lying within transverse hippocampal slices or lamellae [Andersen, Bliss, and
Robert S Sloviter, Terje eLømo
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Relating transformers to models and neural representations of the hippocampal formation [PDF]
arXiv, 2021 Many deep neural network architectures loosely based on brain networks have recently been shown to replicate neural firing patterns observed in the brain. One of the most exciting and promising novel architectures, the Transformer neural network, was developed without the brain in mind.
arxiv