Results 21 to 30 of about 4,772,903 (306)

The hippocampal formation as a hierarchical generative model supporting generative replay and continual learning

Progress in neurobiology, 2020
We advance a novel computational theory of the hippocampal formation as a hierarchical generative model that organizes sequential experiences, such as rodent trajectories during spatial navigation, into coherent spatiotemporal contexts.
Ivilin Peev Stoianov, D. Maisto, G. Pezzulo   +2 more
semanticscholar   +1 more source

Spatial representations in macaque hippocampal formation

bioRxiv, 2020
The hippocampal formation is linked to spatial navigation but direct evidence in primates during active, unconstrained navigation is lacking. Combined with accurate behavioral tracking of eye and head, we record neurons across hippocampal regions in ...
Dun Mao, Dun Mao, Eric Avila, B. Caziot, Jean Laurens, J. Dickman, D. Angelaki, D. Angelaki, D. Angelaki   +8 more
semanticscholar   +1 more source

Cell Proliferation in the Adult Chicken Hippocampus Correlates With Individual Differences in Time Spent in Outdoor Areas and Tonic Immobility

Frontiers in Veterinary Science, 2020
Access to outdoor areas is provided as a means of enhancing welfare in commercial systems for laying hens (Gallus gallus domesticus), but substantial individual differences exist in their proportional use.
Elena A. Armstrong, Elena A. Armstrong, Bernhard Voelkl, Sabine Voegeli, Sabine G. Gebhardt-Henrich, Jonathan H. Guy, Jonathan H. Guy, Victoria Sandilands, Tim Boswell, Tim Boswell, Michael J. Toscano, Tom V. Smulders, Tom V. Smulders   +12 more
doaj   +1 more source

Morphological Variations of Hippocampal Formation in Epilepsy

Pediatric Neurology Briefs, 2013
Researchers at Hospital Sao Paulo and other centers in Brazil compared the hippocampal formation (HF) morphology of healthy asymptomatic individuals (n=30) with that of patients with mesial temporal lobe epilepsy and hippocampal sclerosis (MTLE-HS)(n=68),
J Gordon Millichap
doaj   +1 more source

Framing of grid cells within and beyond navigation boundaries

eLife, 2017
Grid cells represent an ideal candidate to investigate the allocentric determinants of the brain’s cognitive map. Most studies of grid cells emphasized the roles of geometric boundaries within the navigational range of the animal. Behaviors such as novel
Francesco Savelli, JD Luck, James J Knierim   +2 more
doaj   +1 more source

Intermediate levels of hippocampal activity appear optimal for associative memory formation. [PDF]

PLoS ONE, 2010
BACKGROUND: It is well established that hippocampal activity is positively related to effective associative memory formation. However, in biological systems often optimal levels of activity are contrasted by both sub- and supra-optimal levels.
Xiao Liu, Shaozheng Qin, Mark Rijpkema, Jing Luo, Guillén Fernández   +4 more
doaj   +1 more source

Fan cells in lateral entorhinal cortex directly influence medial entorhinal cortex through synaptic connections in layer 1

eLife, 2022
Standard models for spatial and episodic memory suggest that the lateral entorhinal cortex (LEC) and medial entorhinal cortex (MEC) send parallel independent inputs to the hippocampus, each carrying different types of information.
Brianna Vandrey, Jack Armstrong, Christina M Brown, Derek LF Garden, Matthew F Nolan   +4 more
doaj   +1 more source

Spatial cell firing during virtual navigation of open arenas by head-restrained mice

eLife, 2018
We present a mouse virtual reality (VR) system which restrains head-movements to horizontal rotations, compatible with multi-photon imaging. This system allows expression of the spatial navigation and neuronal firing patterns characteristic of real open ...
Guifen Chen, John Andrew King, Yi Lu, Francesca Cacucci, Neil Burgess   +4 more
doaj   +1 more source

Chronic Stress Alters Behavior in the Forced Swim Test and Underlying Neural Activity in Animals Exposed to Alcohol Prenatally: Sex- and Time-Dependent Effects

Frontiers in Behavioral Neuroscience, 2018
Dysregulation of the hypothalamic-pituitary-adrenal (HPA) stress response has been suggested to play a role in vulnerability to stress-related disorders, such as depression.
Vivian Y. Y. Lam, Charlis Raineki, Lily E. Takeuchi, Linda Ellis, Todd S. Woodward, Todd S. Woodward, Joanne Weinberg   +6 more
doaj   +1 more source

Space and Memory (Far) Beyond the Hippocampus: Many Subcortical Structures Also Support Cognitive Mapping and Mnemonic Processing

Frontiers in Neural Circuits, 2019
Memory research remains focused on just a few brain structures—in particular, the hippocampal formation (the hippocampus and entorhinal cortex). Three key discoveries promote this continued focus: the striking demonstrations of enduring anterograde ...
Shane M. O’Mara, John P. Aggleton
doaj   +1 more source