Differential expression of synaptophysin and synaptoporin during pre- and postnatal development of the hippocampal network [PDF]
The closely related synaptic vesicle membrane proteins synaptophysin and synaptoporin are abundant in the hippocampal formation of the adult rat. But the prenatal hippocampal formation contains only synaptophysin, which is first detected at embryonic day
Amaral +51 more
core +1 more source
Meditation effects within the hippocampal complex revealed by voxel-based morphometry and cytoarchitectonic probabilistic mapping. [PDF]
Scientific studies addressing anatomical variations in meditators' brains have emerged rapidly over the last few years, where significant links are most frequently reported with respect to gray matter (GM).
Gaser, Christian +4 more
core +2 more sources
Metabolite alterations in the hippocampus of high-functioning adult subjects with autism [PDF]
The aim of the present study was to investigate metabolite alterations in the hippocampal formation as they relate to aggression in high-functioning adults with autism.
Isoda, Haruo +12 more
core +2 more sources
Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2. [PDF]
BACKGROUND: It is becoming increasingly evident that deficits in the cortex and hippocampus at early stages of dementia in Alzheimer's disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-β peptide (Aβ42).
Alifragis, P +5 more
core +6 more sources
Change in background context disrupts performance on visual paired comparison following hippocampal damage [PDF]
The medial temporal lobe plays a critical role in recognition memory but, within the medial temporal lobe, the precise neural structures underlying recognition memory remain equivocal. in this study, visual paired comparison (VPC) was used to investigate
Bachevalier, J. +3 more
core +3 more sources
Perirhinal cortex and temporal lobe epilepsy
The perirhinal cortex – which is interconnected with several limbic structures and is intimately involved in learning and memory - plays major roles in pathological processes such as the kindling phenomenon of epileptogenesis and the spread of limbic ...
Giuseppe eBiagini +6 more
doaj +1 more source
Physical Activity Reduces Hippocampal Atrophy in Elders at Genetic Risk for Alzheimer\u27s Disease [PDF]
We examined the impact of physical activity (PA) on longitudinal change in hippocampal volume in cognitively intact older adults at varying genetic risk for the sporadic form of Alzheimer\u27s disease (AD). Hippocampal volume was measured from structural
Durgerian, Sally +10 more
core +2 more sources
Entorhinal cortex (EC), fascia dentata (FD), hippocampus (HP), and basal ganglia (BG) were studied in Rett syndrome (RS) cases and compared with control brains and an autism case. Kluver–Barrera and Golgi methods were used. In RS most of the areas of EC,
Tatiana A. Leontovich +3 more
doaj +1 more source
Preliminary Evidence of Increased Hippocampal Myelin Content in Veterans with Posttraumatic Stress Disorder. [PDF]
Recent findings suggest the formation of myelin in the central nervous system by oligodendrocytes is a continuous process that can be modified with experience.
Chao, Linda L +4 more
core +1 more source
Hippocampal lesions impair rapid learning of a continuous spatial alternation task. [PDF]
The hippocampus is essential for the formation of memories for events, but the specific features of hippocampal neural activity that support memory formation are not yet understood.
Steve M Kim, Loren M Frank
doaj +1 more source

