Effect of scopolamine-based amnesia on the number of astrocytes in the rat's hippocampus [PDF]
As neuron-astrocyte interactions play a crucial role in the adult brain, it is thought that astrocytes support learning and memory through specific mechanisms.
Azami, N.S.+2 more
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Memory research remains focused on just a few brain structures—in particular, the hippocampal formation (the hippocampus and entorhinal cortex). Three key discoveries promote this continued focus: the striking demonstrations of enduring anterograde ...
Shane M. O’Mara, John P. Aggleton
doaj +1 more source
Spatial cell firing during virtual navigation of open arenas by head-restrained mice
We present a mouse virtual reality (VR) system which restrains head-movements to horizontal rotations, compatible with multi-photon imaging. This system allows expression of the spatial navigation and neuronal firing patterns characteristic of real open ...
Guifen Chen+4 more
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Establishing the boundaries: the hippocampal contribution to imagining scenes [PDF]
When we visualize scenes, either from our own past or invented, we impose a viewpoint for our “mind's eye” and we experience the resulting image as spatially coherent from that viewpoint.
Bird, Chris M+4 more
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Intermediate levels of hippocampal activity appear optimal for associative memory formation. [PDF]
BACKGROUND: It is well established that hippocampal activity is positively related to effective associative memory formation. However, in biological systems often optimal levels of activity are contrasted by both sub- and supra-optimal levels.
Xiao Liu+4 more
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Meditation effects within the hippocampal complex revealed by voxel-based morphometry and cytoarchitectonic probabilistic mapping. [PDF]
Scientific studies addressing anatomical variations in meditators' brains have emerged rapidly over the last few years, where significant links are most frequently reported with respect to gray matter (GM).
Gaser, Christian+4 more
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Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2. [PDF]
BACKGROUND: It is becoming increasingly evident that deficits in the cortex and hippocampus at early stages of dementia in Alzheimer's disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-β peptide (Aβ42).
Alifragis, P+5 more
core +6 more sources
Framing of grid cells within and beyond navigation boundaries
Grid cells represent an ideal candidate to investigate the allocentric determinants of the brain’s cognitive map. Most studies of grid cells emphasized the roles of geometric boundaries within the navigational range of the animal. Behaviors such as novel
Francesco Savelli+2 more
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Metabolite alterations in the hippocampus of high-functioning adult subjects with autism [PDF]
The aim of the present study was to investigate metabolite alterations in the hippocampal formation as they relate to aggression in high-functioning adults with autism.
Isoda, Haruo+12 more
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Computational models of neural networks can be based on a variety of different parameters. These parameters include, for example, the 3d shape of neuron layers, the neurons' spatial projection patterns, spiking dynamics and neurotransmitter systems ...
Martin ePyka+5 more
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