Results 31 to 40 of about 4,930,687 (268)

Effect of scopolamine-based amnesia on the number of astrocytes in the rat's hippocampus [PDF]

open access: yes, 2012
As neuron-astrocyte interactions play a crucial role in the adult brain, it is thought that astrocytes support learning and memory through specific mechanisms.
Azami, N.S.   +2 more
core   +1 more source

Space and Memory (Far) Beyond the Hippocampus: Many Subcortical Structures Also Support Cognitive Mapping and Mnemonic Processing

open access: yesFrontiers in Neural Circuits, 2019
Memory research remains focused on just a few brain structures—in particular, the hippocampal formation (the hippocampus and entorhinal cortex). Three key discoveries promote this continued focus: the striking demonstrations of enduring anterograde ...
Shane M. O’Mara, John P. Aggleton
doaj   +1 more source

Spatial cell firing during virtual navigation of open arenas by head-restrained mice

open access: yeseLife, 2018
We present a mouse virtual reality (VR) system which restrains head-movements to horizontal rotations, compatible with multi-photon imaging. This system allows expression of the spatial navigation and neuronal firing patterns characteristic of real open ...
Guifen Chen   +4 more
doaj   +1 more source

Establishing the boundaries: the hippocampal contribution to imagining scenes [PDF]

open access: yes, 2010
When we visualize scenes, either from our own past or invented, we impose a viewpoint for our “mind's eye” and we experience the resulting image as spatially coherent from that viewpoint.
Bird, Chris M   +4 more
core   +1 more source

Intermediate levels of hippocampal activity appear optimal for associative memory formation. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: It is well established that hippocampal activity is positively related to effective associative memory formation. However, in biological systems often optimal levels of activity are contrasted by both sub- and supra-optimal levels.
Xiao Liu   +4 more
doaj   +1 more source

Meditation effects within the hippocampal complex revealed by voxel-based morphometry and cytoarchitectonic probabilistic mapping. [PDF]

open access: yes, 2013
Scientific studies addressing anatomical variations in meditators' brains have emerged rapidly over the last few years, where significant links are most frequently reported with respect to gray matter (GM).
Gaser, Christian   +4 more
core   +2 more sources

Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2. [PDF]

open access: yes, 2012
BACKGROUND: It is becoming increasingly evident that deficits in the cortex and hippocampus at early stages of dementia in Alzheimer's disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-β peptide (Aβ42).
Alifragis, P   +5 more
core   +6 more sources

Framing of grid cells within and beyond navigation boundaries

open access: yeseLife, 2017
Grid cells represent an ideal candidate to investigate the allocentric determinants of the brain’s cognitive map. Most studies of grid cells emphasized the roles of geometric boundaries within the navigational range of the animal. Behaviors such as novel
Francesco Savelli   +2 more
doaj   +1 more source

Metabolite alterations in the hippocampus of high-functioning adult subjects with autism [PDF]

open access: yes, 2009
The aim of the present study was to investigate metabolite alterations in the hippocampal formation as they relate to aggression in high-functioning adults with autism.
Isoda, Haruo   +12 more
core   +2 more sources

Parametric Anatomical Modeling: A method for modeling the anatomical layout of neurons and their projections

open access: yesFrontiers in Neuroanatomy, 2014
Computational models of neural networks can be based on a variety of different parameters. These parameters include, for example, the 3d shape of neuron layers, the neurons' spatial projection patterns, spiking dynamics and neurotransmitter systems ...
Martin ePyka   +5 more
doaj   +1 more source

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