Results 41 to 50 of about 242,255 (327)

Resistance of CA1 pyramidal cells to STZ-induced diabetes in young rats [PDF]

open access: yes, 2009
The pyramidal cell density of CA1 hippocampal subfield following STZ-induced diabetes in young rats were studied. 12 male albino 6-week Wistar rats were allocated equally in groups of normal and diabetic. Hyperglycemia induced by Streptozotocin (80 mg/kg)
Behnampour, N.   +5 more
core   +1 more source

Adult Hippocampal Neurogenesis: Regulation and Possible Functional and Clinical Correlates

open access: yesFrontiers in Neuroanatomy, 2018
The formation of new neurons in the adult central nervous system (CNS) has been recognized as one of the major findings in neuroanatomical research. The hippocampal formation (HF), one of the main targets of these investigations, holds a neurogenic niche
Pedro Baptista   +2 more
doaj   +1 more source

Differential ripple propagation along the hippocampal longitudinal axis

open access: yeseLife, 2023
Hippocampal ripples are highly synchronous neural events critical for memory consolidation and retrieval. A minority of strong ripples has been shown to be of particular importance in situations of increased memory demands.
Roberto De Filippo, Dietmar Schmitz
doaj   +1 more source

The GDNF-GFRα1 complex promotes the development of hippocampal dendritic arbors and spines via NCAM [PDF]

open access: yes, 2016
The formation of synaptic connections during nervous system development requires the precise control of dendrite growth and synapse formation. Although glial cell line-derived neurotrophic factor (GDNF) and its receptor GFRα1 are expressed in the ...
Alsina, Fernando Cruz   +5 more
core   +2 more sources

Updating the lamellar hypothesis of hippocampal organization

open access: yesFrontiers in Neural Circuits, 2012
In 1971, Andersen and colleagues proposed that excitatory activity in the entorhinal cortex propagates topographically to the dentate gyrus, and on through a trisynaptic circuit lying within transverse hippocampal slices or lamellae [Andersen, Bliss, and
Robert S Sloviter, Terje eLømo
doaj   +1 more source

A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory

open access: yesNature Communications, 2022
The mammalian hippocampal formation plays a key role in several higher brain functions. Here, the authors show that excitatory neurons in layer 6b of the mouse EC project to all sub-regions comprising the hippocampal formation and receive input from the ...
Yoav Ben-Simon   +5 more
doaj   +1 more source

Hippocampal Somatostatin Interneurons, Long-Term Synaptic Plasticity and Memory

open access: yesFrontiers in Neural Circuits, 2021
A distinctive feature of the hippocampal structure is the diversity of inhibitory interneurons. These complex inhibitory interconnections largely contribute to the tight modulation of hippocampal circuitry, as well as to the formation and coordination of
Eve Honoré   +3 more
doaj   +1 more source

Effects of hippocampal damage on reward threshold and response rate during self-stimulation of the ventral tegmental area in the rat [PDF]

open access: yes, 1999
The main purpose of this study was to explore the role of the hippocampus in motivated behavior. Rats with bilateral excitotoxic lesions of the hippocampus and controls were trained to lever press for electrical stimulation of the ventral tegmental area.
Altman   +52 more
core   +1 more source

Navigation Patterns and Scent Marking: Underappreciated Contributors to Hippocampal and Entorhinal Spatial Representations?

open access: yesFrontiers in Behavioral Neuroscience, 2018
According to the currently prevailing theory, hippocampal formation constructs and maintains cognitive spatial maps. Most of the experimental evidence for this theory comes from the studies on navigation in laboratory rats and mice, typically male ...
Mikhail A. Lebedev   +3 more
doaj   +1 more source

Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration. [PDF]

open access: yes, 2016
Mechanistic studies of axon growth during development are beneficial to the search for neuron-intrinsic regulators of axon regeneration. Here, we discovered that, in the developing neuron from rat, Akt signaling regulates axon growth and growth cone ...
Ahn, Jee-Yin   +9 more
core   +2 more sources

Home - About - Disclaimer - Privacy