Results 41 to 50 of about 5,022,712 (233)

Resistance of CA1 pyramidal cells to STZ-induced diabetes in young rats [PDF]

open access: yes, 2009
The pyramidal cell density of CA1 hippocampal subfield following STZ-induced diabetes in young rats were studied. 12 male albino 6-week Wistar rats were allocated equally in groups of normal and diabetic. Hyperglycemia induced by Streptozotocin (80 mg/kg)
Behnampour, N.   +5 more
core   +1 more source

Updating the lamellar hypothesis of hippocampal organization

open access: yesFrontiers in Neural Circuits, 2012
In 1971, Andersen and colleagues proposed that excitatory activity in the entorhinal cortex propagates topographically to the dentate gyrus, and on through a trisynaptic circuit lying within transverse hippocampal slices or lamellae [Andersen, Bliss, and
Robert S Sloviter, Terje eLømo
doaj   +1 more source

A direct excitatory projection from entorhinal layer 6b neurons to the hippocampus contributes to spatial coding and memory

open access: yesNature Communications, 2022
The mammalian hippocampal formation plays a key role in several higher brain functions. Here, the authors show that excitatory neurons in layer 6b of the mouse EC project to all sub-regions comprising the hippocampal formation and receive input from the ...
Yoav Ben-Simon   +5 more
doaj   +1 more source

Differential ripple propagation along the hippocampal longitudinal axis

open access: yeseLife, 2023
Hippocampal ripples are highly synchronous neural events critical for memory consolidation and retrieval. A minority of strong ripples has been shown to be of particular importance in situations of increased memory demands.
Roberto De Filippo, Dietmar Schmitz
doaj   +1 more source

The GDNF-GFRα1 complex promotes the development of hippocampal dendritic arbors and spines via NCAM [PDF]

open access: yes, 2016
The formation of synaptic connections during nervous system development requires the precise control of dendrite growth and synapse formation. Although glial cell line-derived neurotrophic factor (GDNF) and its receptor GFRα1 are expressed in the ...
Alsina, Fernando Cruz   +5 more
core   +2 more sources

Loss of Immunohistochemical Reactivity in Association With Handling-Induced Dark Neurons in Mouse Brains. [PDF]

open access: yes, 2020
The handling-induced dark neuron is a histological artifact observed in brain samples handled before fixation with aldehydes. To explore associations between dark neurons and immunohistochemical alterations in mouse brains, we examined protein products ...
Chang, Rachel C   +5 more
core  

Hippocampus-dependent emergence of spatial sequence coding in retrosplenial cortex. [PDF]

open access: yes, 2018
Retrosplenial cortex (RSC) is involved in visuospatial integration and spatial learning, and RSC neurons exhibit discrete, place cell-like sequential activity that resembles the population code of space in hippocampus.
Bonin, Vincent   +5 more
core   +2 more sources

An allocentric human odometer for perceiving distances on the ground plane

open access: yeseLife
We reliably judge locations of static objects when we walk despite the retinal images of these objects moving with every step we take. Here, we showed our brains solve this optical illusion by adopting an allocentric spatial reference frame.
Liu Zhou   +3 more
doaj   +1 more source

The retrosplenial cortex: intrinsic connectivity and connections with the (para)hippocampal region in the rat. An interactive connectome.

open access: yesFrontiers in Neuroinformatics, 2011
A connectome is an indispensable tool for brain researchers, since it quickly provides comprehensive knowledge of the brain’s anatomical connections. Such knowledge lies at the basis of understanding network functions.
Jorgen eSugar   +3 more
doaj   +1 more source

A Putative Role for Ubiquitin-Proteasome Signaling in Estrogenic Memory Regulation

open access: yesFrontiers in Behavioral Neuroscience, 2022
Sex steroid hormones such as 17β-estradiol (E2) are critical neuromodulators of hippocampal synaptic plasticity and hippocampus-dependent memory in both males and females.
Sarah B. Beamish, Karyn M. Frick
doaj   +1 more source

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