Results 51 to 60 of about 242,255 (327)
An allocentric human odometer for perceiving distances on the ground plane
eLifeWe reliably judge locations of static objects when we walk despite the retinal images of these objects moving with every step we take. Here, we showed our brains solve this optical illusion by adopting an allocentric spatial reference frame.
Liu Zhou +3 more
doaj +1 more source
Frontiers in Veterinary Science, 2019 The hippocampal formation (HF) is a relevant brain structure that is involved in several neurological and psychiatric diseases. In cats, structural changes of the HF are associated with epilepsy.
Isabella Gruber +3 more
doaj +1 more source
A Putative Role for Ubiquitin-Proteasome Signaling in Estrogenic Memory Regulation
Frontiers in Behavioral Neuroscience, 2022 Sex steroid hormones such as 17β-estradiol (E2) are critical neuromodulators of hippocampal synaptic plasticity and hippocampus-dependent memory in both males and females.
Sarah B. Beamish, Karyn M. Frick
doaj +1 more source
Loss of Immunohistochemical Reactivity in Association With Handling-Induced Dark Neurons in Mouse Brains. [PDF]
, 2020 The handling-induced dark neuron is a histological artifact observed in brain samples handled before fixation with aldehydes. To explore associations between dark neurons and immunohistochemical alterations in mouse brains, we examined protein products ...
Chang, Rachel C +5 more
core
Normal and Amnesic Learning, Recognition, and Memory by a Neural Model of Cortico-Hippocampal Interactions [PDF]
, 1993 The processes by which humans and other primates learn to recognize objects have been the subject of many models. Processes such as learning, categorization, attention, memory search, expectation, and novelty detection work together at different stages ...
Carpenter, Gail A., Grossberg, Stephen
core +2 more sources
Rabphilin-3A Drives Structural Modifications of Dendritic Spines Induced by Long-Term Potentiation
Cells, 2022 The interaction of Rabphilin-3A (Rph3A) with the NMDA receptor (NMDAR) in hippocampal neurons plays a pivotal role in the synaptic retention of this receptor.
Luca Franchini +6 more
doaj +1 more source
Granule Cell Dispersion in Human Temporal Lobe Epilepsy: Proteomics investigation of neurodevelopmental migratory pathways [PDF]
, 2020 Granule cell dispersion (GCD) is a common pathological feature observed in the hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms underlying GCD remain to be elucidated, but one hypothesis proposes aberrant reactivation of
Al-Kaaby, B. +11 more
core +1 more source
Frontiers in Neuroanatomy, 2014 Computational models of neural networks can be based on a variety of different parameters. These parameters include, for example, the 3d shape of neuron layers, the neurons' spatial projection patterns, spiking dynamics and neurotransmitter systems ...
Martin ePyka +5 more
doaj +1 more source
Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability [PDF]
, 2017 Oligophrenin-1 (OPHN1) is a Rho GTPase activating protein whose mutations cause X-linked intellectual disability (XLID). How loss of function of Ophnl affects neuronal development is only partly understood.
Allegra, M +7 more
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source