Results 81 to 90 of about 4,930,687 (268)
A connectome is an indispensable tool for brain researchers, since it quickly provides comprehensive knowledge of the brain’s anatomical connections. Such knowledge lies at the basis of understanding network functions.
Jorgen eSugar+3 more
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Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability [PDF]
Oligophrenin-1 (OPHN1) is a Rho GTPase activating protein whose mutations cause X-linked intellectual disability (XLID). How loss of function of Ophnl affects neuronal development is only partly understood.
Allegra, M+7 more
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Neurofibrillary tangles and dystrophic neurites appear to develop in a highly characteristic spatial and temporal sequence in AD. In order to examine the nature of the cellular progression we have studied the trisynaptic entorhinal, dentate gyrus, CA3/4 ...
Joseph H. Su+2 more
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Neurogenesis in the neonatal rat hippocampus is regulated by sexually dimorphic epigenetic modifiers
Highlights Neurogenesis in the dentate gyrus peaks in the early postnatal period and in the laboratory rat is significantly greater in males than females. Here we report divergent regulation of cell genesis in the neonatal dentate gyrus.
S. L. Stockman+3 more
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Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats
In the rat hippocampal formation, degeneration of CA4-derived afferent fibers provokes the growth of mossy fiber collaterals into the fascia dentata. These aberrant fibers subsequently form granule cell-granule cell synapses.
D. Tauck, J. Nadler
semanticscholar +1 more source
Awake Reactivation of Prior Experiences Consolidates Memories and Biases Cognition. [PDF]
After experiences are encoded into memory, post-encoding reactivation mechanisms have been proposed to mediate long-term memory stabilization and transformation.
Davachi, Lila, Tambini, Arielle
core +2 more sources
Early life stress (ELS) is associated with an increased risk for neuropsychiatric disorders, and both neuroinflammation and mitochondrial dysfunction seem to be central to mental health.
Diego San Felipe+7 more
doaj +1 more source
Normal and Amnesic Learning, Recognition, and Memory by a Neural Model of Cortico-Hippocampal Interactions [PDF]
The processes by which humans and other primates learn to recognize objects have been the subject of many models. Processes such as learning, categorization, attention, memory search, expectation, and novelty detection work together at different stages ...
Carpenter, Gail A., Grossberg, Stephen
core +2 more sources
Axonal regeneration in hippocampal and spinal cord organotypic slice cultures [PDF]
Under normal conditions, axonal regeneration after lesions is not possible in mature CNS but can occur in embryonic and early postnatal nervous systems. In recent years, a number of possible strategies to enhance axonal regeneration and eventually treat ...
Bonnici, Brenda
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Hippocampus-dependent emergence of spatial sequence coding in retrosplenial cortex. [PDF]
Retrosplenial cortex (RSC) is involved in visuospatial integration and spatial learning, and RSC neurons exhibit discrete, place cell-like sequential activity that resembles the population code of space in hippocampus.
Bonin, Vincent+5 more
core +2 more sources