Results 171 to 180 of about 41,599 (208)
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Hippocampal sclerosis revisited
Brain and Development, 1998Studies dating back more than 150 years reported a relationship between hippocampal sclerosis and epilepsy. Retrospective studies of patients who underwent temporal lobectomy for intractable partial epilepsy found a relationship between a history of early childhood convulsions, hippocampal sclerosis, and the development of temporal lobe epilepsy.
P D, Fisher, E F, Sperber, S L, Moshé
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Update on Hippocampal Sclerosis
Current Neurology and Neuroscience Reports, 2015The diagnostic hallmarks of hippocampal sclerosis (HS) are severe volume loss of the hippocampus, severe neuronal loss, and reactive gliosis involving primarily two especially vulnerable fields, CA1 and the subiculum. Occasionally, HS may be the only neuropathological change detected in older individuals with dementia and is known as pure HS.
Juliana R, Dutra +2 more
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Neuropathology of Hippocampal Sclerosis
2008Publisher Summary This chapter emphasizes that hippocampal sclerosis (HS), which is a selective neuronal loss and gliosis in the CA1 sector and the subiculum, is often observed in the elderly at the post mortem examination. In many patients who present with dementia, HS coexists with various other types of pathologies, including Alzheimer's disease ...
Catalina, Amador-Ortiz +1 more
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2019
Abstract Temporal lobe epilepsy (TLE) is the most common form of adult localization-related epilepsy and 80% of these cases originate in the hippocampus. Hippocampal sclerosis (HS) is the single most common cause of medically refractory epilepsy that is also amenable to surgery and is a combination of astrogliosis and atrophy throughout ...
Zoe E. Teton, Ahmed M. Raslan
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Abstract Temporal lobe epilepsy (TLE) is the most common form of adult localization-related epilepsy and 80% of these cases originate in the hippocampus. Hippocampal sclerosis (HS) is the single most common cause of medically refractory epilepsy that is also amenable to surgery and is a combination of astrogliosis and atrophy throughout ...
Zoe E. Teton, Ahmed M. Raslan
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Hippocampal sclerosis without detectable hippocampal atrophy
Neurology, 1994Six patients from three centers had MRI and pathologic evidence of hippocampal sclerosis but no detectable hippocampal atrophy. Loss of normal internal structure and T1- and T2-weighted signal abnormalities allowed the MRI diagnosis of unilateral hippocampal sclerosis when hippocampal volume measurements were normal and symmetric.
G D, Jackson +2 more
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Neurology, 2007
Temporal lobe epilepsy is the most commonly encountered partial epilepsy syndrome in adults. Many patients are refractory to medications and therefore considered for surgical treatment. Pathologic series and modern imaging demonstrate evidence of hippocampal (mesial temporal) sclerosis (HS), characterized by cell loss in the hippocampal pyramidal cell ...
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Temporal lobe epilepsy is the most commonly encountered partial epilepsy syndrome in adults. Many patients are refractory to medications and therefore considered for surgical treatment. Pathologic series and modern imaging demonstrate evidence of hippocampal (mesial temporal) sclerosis (HS), characterized by cell loss in the hippocampal pyramidal cell ...
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Hippocampal sclerosis—Origins and imaging
Epilepsia, 2012SummaryThe association between hippocampal sclerosis (HS) and epilepsy has been known for almost two centuries. For many years, HS was studied in postmortem series; however, since the mid‐20th century, surgical specimens from temporal lobe resections have provided important new knowledge. HS is the most common pathology underlying drug‐resistant mesial
Kristina, Malmgren, Maria, Thom
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Hippocampal sclerosis in association with neurocysticercosis
Epileptic Disorders, 2007ABSTRACT Objective To discuss the possible mechanisms underlying a dual pathology combining neurocysticercosis and hippocampal atrophy, illustrated by the observation of four patients with epilepsy. Case reports.
Monika, Singla +4 more
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Hippocampal Sclerosis and Human Memory
Archives of Neurology, 1993To study the effects of hippocampal sclerosis on preoperative neuropsychological memory tests.Analyses of variance and chi 2 tests were used to compare patient groups (divided retrospectively) with a control group.Hospital epilepsy unit.All patients who underwent a temporal lobectomy for intractable seizure relief during the preceding 18 months were ...
L A, Miller, D G, Muñoz, M, Finmore
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Epilepsies associated with hippocampal sclerosis
Acta Neuropathologica, 2014Hippocampal sclerosis (HS) is considered the most frequent neuropathological finding in patients with mesial temporal lobe epilepsy (MTLE). Hippocampal specimens of pharmacoresistant MTLE patients that underwent epilepsy surgery for seizure control reveal the characteristic pattern of segmental neuronal cell loss and concomitant astrogliosis.
Fernando, Cendes +4 more
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