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Medicinska istrazivanja, 2023
Hippocampal sclerosis is one of the most common causes of focal epilepsy. At the same time, hippocampal sclerosis is the most common surgical substrate in focal pharmacoresistant epilepsies. The hippocampus has a specific anatomical structure consisting of a total of four sectors.
Aleksandar Ristić +4 more
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Hippocampal sclerosis is one of the most common causes of focal epilepsy. At the same time, hippocampal sclerosis is the most common surgical substrate in focal pharmacoresistant epilepsies. The hippocampus has a specific anatomical structure consisting of a total of four sectors.
Aleksandar Ristić +4 more
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2012
Hippocampal sclerosis (HS) represents the most common neuropathological finding in patients undergoing surgery for intractable temporal lobe epilepsy (TLE). Recent neuropathological and clinical observations indicate that HS is not always a uniform entity.
Özkara, Çiǧdem, Aronica, Eleonora
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Hippocampal sclerosis (HS) represents the most common neuropathological finding in patients undergoing surgery for intractable temporal lobe epilepsy (TLE). Recent neuropathological and clinical observations indicate that HS is not always a uniform entity.
Özkara, Çiǧdem, Aronica, Eleonora
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Hippocampal sclerosis revisited
Brain and Development, 1998Studies dating back more than 150 years reported a relationship between hippocampal sclerosis and epilepsy. Retrospective studies of patients who underwent temporal lobectomy for intractable partial epilepsy found a relationship between a history of early childhood convulsions, hippocampal sclerosis, and the development of temporal lobe epilepsy.
P D, Fisher, E F, Sperber, S L, Moshé
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2019
Abstract Temporal lobe epilepsy (TLE) is the most common form of adult localization-related epilepsy and 80% of these cases originate in the hippocampus. Hippocampal sclerosis (HS) is the single most common cause of medically refractory epilepsy that is also amenable to surgery and is a combination of astrogliosis and atrophy throughout ...
Zoe E. Teton, Ahmed M. Raslan
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Abstract Temporal lobe epilepsy (TLE) is the most common form of adult localization-related epilepsy and 80% of these cases originate in the hippocampus. Hippocampal sclerosis (HS) is the single most common cause of medically refractory epilepsy that is also amenable to surgery and is a combination of astrogliosis and atrophy throughout ...
Zoe E. Teton, Ahmed M. Raslan
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Neuropathology of Hippocampal Sclerosis
2008Publisher Summary This chapter emphasizes that hippocampal sclerosis (HS), which is a selective neuronal loss and gliosis in the CA1 sector and the subiculum, is often observed in the elderly at the post mortem examination. In many patients who present with dementia, HS coexists with various other types of pathologies, including Alzheimer's disease ...
Catalina, Amador-Ortiz +1 more
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Hippocampal sclerosis without detectable hippocampal atrophy
Neurology, 1994Six patients from three centers had MRI and pathologic evidence of hippocampal sclerosis but no detectable hippocampal atrophy. Loss of normal internal structure and T1- and T2-weighted signal abnormalities allowed the MRI diagnosis of unilateral hippocampal sclerosis when hippocampal volume measurements were normal and symmetric.
G D, Jackson +2 more
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Neurology, 2007
Temporal lobe epilepsy is the most commonly encountered partial epilepsy syndrome in adults. Many patients are refractory to medications and therefore considered for surgical treatment. Pathologic series and modern imaging demonstrate evidence of hippocampal (mesial temporal) sclerosis (HS), characterized by cell loss in the hippocampal pyramidal cell ...
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Temporal lobe epilepsy is the most commonly encountered partial epilepsy syndrome in adults. Many patients are refractory to medications and therefore considered for surgical treatment. Pathologic series and modern imaging demonstrate evidence of hippocampal (mesial temporal) sclerosis (HS), characterized by cell loss in the hippocampal pyramidal cell ...
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Epilepsies associated with hippocampal sclerosis
Acta Neuropathologica, 2014Hippocampal sclerosis (HS) is considered the most frequent neuropathological finding in patients with mesial temporal lobe epilepsy (MTLE). Hippocampal specimens of pharmacoresistant MTLE patients that underwent epilepsy surgery for seizure control reveal the characteristic pattern of segmental neuronal cell loss and concomitant astrogliosis.
Fernando, Cendes +4 more
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Hippocampal Sclerosis and Human Memory
Archives of Neurology, 1993To study the effects of hippocampal sclerosis on preoperative neuropsychological memory tests.Analyses of variance and chi 2 tests were used to compare patient groups (divided retrospectively) with a control group.Hospital epilepsy unit.All patients who underwent a temporal lobectomy for intractable seizure relief during the preceding 18 months were ...
L A, Miller, D G, Muñoz, M, Finmore
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