Results 201 to 210 of about 81,056 (343)

In severe ADNC, hippocampi with comorbid LATE-NC and hippocampal sclerosis have substantially more astrocytosis than those with LATE-NC or hippocampal sclerosis alone. [PDF]

J Neuropathol Exp Neurol, 2023
Niedowicz DM, Katsumata Y, Nelson PT.
europepmc   +1 more source

The patient had a normal magnetic resonance imaging and temporal lobe epilepsy secondary to a porencephalic cyst but showed structural lesions (hippocampal sclerosis)

, 2013
Teppei Matsubara, Satoshi Ayuzawa, Tsukasa Aoki, Ayataka Fujiomto, Satoru Osuka, Akira Matsumura   +5 more
openalex   +1 more source

Treatment of pediatric epilepsy

Pediatric Investigation, EarlyView.
Anti‐seizure medications are the first‐line treatment for the vast majority of children with epilepsy, with the advantages of non‐invasive wide adaptability. Surgery is the main treatment for drug‐resistant epilepsy and lesion‐related epilepsy, which can cure some cases of epilepsy in children. A ketogenic diet is often an add‐on therapy.
Junxiao Li, Tinghong Liu, Chang Liu, Jie Deng, Shijie Wu, Suhui Kuang, Xiaotong Li, Zhirong Wei, Shuli Liang   +8 more
wiley   +1 more source

Automatic detection of hippocampal sclerosis in patients with epilepsy. [PDF]

Epilepsia
Belke M, Zahnert F, Steinbrenner M, Halimeh M, Miron G, Tsalouchidou PE, Linka L, Keil B, Jansen A, Möschl V, Kemmling A, Nimsky C, Rosenow F, Menzler K, Knake S.   +14 more
europepmc   +1 more source

Constellation of psychic symptoms in one patient with mesial temporal lobe epilepsy with hippocampal sclerosis and the artistic representation of the patient’s pre and post surgical experiences

Reinaldo Garcia Arismendi, John Kerrison, Gustavo A Garcia-Arismendi   +2 more
openalex   +2 more sources

Hippocampal Sclerosis in Older Patients: Practical Examples and Guidance With a Focus on Cerebral Age-Related TDP-43 With Sclerosis

, 2017
Matthew D. Cykowski, Suzanne Z. Powell, Paul E. Schulz, Hidehiro Takei, Andreana L. Rivera, Robert E. Jackson, Gustavo C. Román, Gregory A. Jicha, Peter T. Nelson   +8 more
openalex   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

Common neuropathologic change drivers of hippocampal sclerosis of ageing. [PDF]

Brain
Woodworth DC, Lou JJ, Yong WH, Head E, Corrada MM, Nelson PT, Sajjadi SA.   +6 more
europepmc   +1 more source

Homo sapiens, industrialisation and the environmental mismatch hypothesis

Biological Reviews, EarlyView.
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley   +1 more source

Hippocampal Sclerosis, Argyrophilic Grain Disease, and Primary Age-Related Tauopathy

, 2019
Gregory A. Jicha, Peter T. Nelson
openalex   +2 more sources