A guide to neuromodulation in drug‐resistant epilepsy
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh +10 more
wiley +1 more source
Drp1-Dependent Mitochondrial Fission in the Hippocampus Drives Chronic Stress-Induced Depressive-like Behaviors in Mice. [PDF]
Peng Q +7 more
europepmc +1 more source
Connectivity of the right cerebello-left hippocampal circuit across adulthood. [PDF]
Hicks TH, Magalhães TNC, Bernard JA.
europepmc +1 more source
Stress disrupts hippocampal integration of overlapping events and memory inference in humans. [PDF]
Schüren KA +5 more
europepmc +1 more source
Abstract Ictal eye closure is commonly associated with functional seizures but may also occur in epileptic seizures. We retrospectively reviewed 113 consecutive stereo‐EEG (SEEG) recordings from adults with drug‐resistant focal epilepsy (2015–2024) to identify prolonged bilateral eye closure during seizures.
Paola Vassallo +10 more
wiley +1 more source
Predicting post‐surgical visuospatial memory performance in people with drug‐resistant epilepsy
Abstract Objective Although verbal memory decline has been consistently reported following surgery for temporal lobe epilepsy, especially when surgery is performed in the language‐dominant hemisphere and targets mesial temporal structures, the relation between the location and the hemisphere of surgery on visuospatial memory, as well as the factors ...
Emma Colucci +7 more
wiley +1 more source
Oxytocin Neuron-Specific CAPS2 Deficiency in Mice Impairs Hippocampal Plasticity and Long-Term Memory Through Reduced ERK Phosphorylation in the Ventral hippocampus. [PDF]
Nagano W +6 more
europepmc +1 more source
Abstract Objective Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy. The molecular heterogeneity underlying DRE remains poorly defined, largely due to limited access to resected brain tissue and substantial genetic diversity.
Yanping Weng +11 more
wiley +1 more source
mTOR Activation Is Required for the Proliferation of Reactive Astrocytes in the Hippocampus During Traumatic Brain Injury. [PDF]
Pradhan LK, Wang X, Yuan F, Gao X.
europepmc +1 more source
Abstract Objective Surgical resection for epilepsy seeks to maximize seizure freedom while minimizing new neurocognitive impairments. Tailored resections guided by anatomoelectroclinical (AEC) hypotheses offer the possibility of sparing parts of the hippocampus.
Eliza M. Reedy +9 more
wiley +1 more source

