Results 231 to 240 of about 633,597 (336)

Olfactory Impairment and Incident Cognitive Decline: A Systematic Review and Meta‐Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory impairment (OI) is associated with poor ageing outcomes. While cross‐sectional studies found a high prevalence of OI among patients with neurodegenerative diseases, the temporal relationship remains unclear. This meta‐analysis aims to synthesise the longitudinal association of OI with cognitive decline (CD). Methods PubMed,
Brian Sheng Yep Yeo, Harris Jun Jie Muhammad Danial Song, Benjamin Kye Jyn Tan, Adithya Suresh, Owen Tsung Wen Ho, Jun He Chan, Esther Yanxin Gao, Claire Jing‐Wen Tan, Chong Boon Teo, Christopher Li‐Hsian Chen, Laura Tay, Ecosse L. Lamoureux, Thomas Hummel, Anna See, Shuhui Xu, Song Tar Toh, Tze Choong Charn, Neville Wei Yang Teo   +17 more
wiley   +1 more source

Chronic Sleep Fragmentation Differentially Affects Alzheimer's Disease Pathology in Male and Female APP^SAA Knock-in Mice. [PDF]

J Inflamm Res
Hawkins MR, Whitlock HR, Johnson CE, Macheda T, Cox MF, Lapid MG, Roberts KN, Hash HM, Drinkard EG, Sunderam S, O'Hara BF, Murphy MP, Duncan MJ, Bachstetter AD.   +13 more
europepmc   +1 more source

Hypophysectomy increases vasoactive intestinal peptide-stimulated cyclic AMP generation in the hippocampus of the rat [PDF]

, 1987
A L Harrelson, BS McEwen
openalex   +1 more source

A potential strategy for improving offspring behavior in maternal immune activation: Amantadine‐mediated suppression of neuroinflammation

Animal Models and Experimental Medicine, EarlyView.
Amantadine (AMA) regulates neurocyte apoptosis and inhibits neurocyte inflammation to prevent maternal immune activation (MIA) from affecting offspring behavior. Abstract Background Maternal viral infection during pregnancy can lead to maternal immune activation (MIA), increasing the risk of neurodevelopmental disorders in offspring.
Jianfei Wu, Yu Liu, Binglong Wang, Yilin Wang, Bo Liu, Youguo Tan, Duanfang Cai, Kezhi Liu, Daixu Wei   +8 more
wiley   +1 more source

Metformin Induces Changes in Sphingosine-1-Phosphate-Related Signaling in Diabetic Mice Brain. [PDF]

Int J Mol Sci
Wencel PL, Czubowicz K, Gewartowska M, Frontczak-Baniewicz M, Strosznajder RP.   +4 more
europepmc   +1 more source

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu, Zhiyang Zeng, Xinyu Ming, Shuming Yin, Yuting Guan, Liangcai Gao, Dali Li   +6 more
wiley   +1 more source

Optogenetic stimulation of midbrain dopaminergic neurons rescues hippocampal synaptic plasticity deficits in a mouse model of Alzheimer's disease. [PDF]

Transl Psychiatry
Ficchì S, Cauzzi E, La Barbera L, De Paolis ML, Loffredo G, Spoleti E, Ferrari I, Saba L, Biamonte F, Nobili A, Krashia P, D'Amelio M.   +11 more
europepmc   +1 more source

Pharmacologically distinct actions of serotonin on single pyramidal neurones of the rat hippocampus recorded in vitro.

, 1987
Rodrigo Andrade, Roger A. Nicoll
openalex   +2 more sources

Long-term atropine treatment lowers the efficacy of carbachol to stimulate phosphatidylinositol breakdown in the cerebral cortex and hippocampus of rats [PDF]

, 1988
L Goobar, Tamás Bartfai
openalex   +1 more source

Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline

Annals of Neurology, EarlyView.
Objective To investigate how sex and age at menopause influence the interplay between Alzheimer's disease (AD) and Lewy body disease (LBD) neuropathologies, and their associations with cognitive decline. Methods We analyzed data from: (1) three Rush Alzheimer's Disease Center cohorts (i.e., the Religious Orders Study, Rush Memory and Aging Project, and
Madeline Wood Alexander, D. Luke Fischer, Lawren VandeVrede, Emma Nichols, Lei Yu, James R. Pike, Walter Swardfager, Che‐Yuan Wu, Mario Masellis, Liisa A. M. Galea, Katherine Zukotynski, Gillian Einstein, Sandra E. Black, Lisa L. Barnes, Julie A. Schneider, Zoe Arvanitakis, Kaitlin B. Casaletto, Jennifer S. Rabin   +17 more
wiley   +1 more source