Results 301 to 310 of about 601,318 (311)

Chronic stress induces depression-like behaviors and Parkinsonism via upregulating α-synuclein. [PDF]

NPJ Parkinsons Dis
Xia D, Xiong M, Yang Y, Wang X, Chen Q, Li S, Meng L, Zhang Z.   +7 more
europepmc   +1 more source

Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice

Glia, EarlyView.
Spatial transcriptomic analysis unravels the mechanisms by which HDACi ameliorates neuroinflammation and enhances neuroprotection by modulating the expression of microglial transcriptomes in the ischemic mouse brain. ABSTRACT Ischemic stroke significantly contributes to global morbidity and disability through a cascade of neurological responses ...
Kevin Jayaraj, Ritesh Kumar, Sukanya Shyamasundar, Thiruma V. Arumugam, Jai S. Polepalli, S. Thameem Dheen   +5 more
wiley   +1 more source

Transient receptor potential vanilloid 4 blockage attenuates pyroptosis in hippocampus of mice following pilocarpine‑induced status epilepticus. [PDF]

Acta Neuropathol Commun
Liu L, Wang Y, Wang X, Zhang G, Sha S, Zhou R, Du Y, Wu C, Chen L.   +8 more
europepmc   +1 more source

What Does Iron Mean to an Oligodendrocyte?

Glia, EarlyView.
ABSTRACT Iron is essential for life and plays a key role in multiple fundamental cellular functions. The brain has the highest rate of energy consumption, and within the brain, oligodendrocytes have the highest level of oxidative metabolism per volume. Oligodendrocytes also stain the strongest for iron.
Quinn W. Wade, James R. Connor
wiley   +1 more source

Astrocyte-derived CCL5-mediated CCR5⁺ neutrophil infiltration drives depression pathogenesis. [PDF]

Sci Adv
Yao H, Jiang SY, Jiao YY, Zhou ZY, Zhu Z, Wang C, Zhang KZ, Ma TF, Hu G, Du RH, Lu M.   +10 more
europepmc   +1 more source

Hippocampal NLRP1 inflammasome mediates anxiety-like behavior in mice with hypothyroidism. [PDF]

Sci Rep
Cheng YW, Zou ZH, Lou CL, Tong MR, Li JK, Zhu WH, Lu YL, Zhu DF, Xu Q, Xu YX.   +9 more
europepmc   +1 more source

Evaluation of the Alterations in Central Cholinergic Neurotransmission in Aging and Amyloid Precursor Protein Knock-In Mice. [PDF]

J Neurochem
Nagai-Arakawa I, Muramatsu I, Uwada J, Tsuda Y, Tokunaga A, Irie A, Maeda H, Madokoro Y, Sato T, Uchida Y, Saito T, Saido TC, Sada K, Masuoka T, Matsukawa N.   +14 more
europepmc   +1 more source

Effect of Fangxia-Dihuang Decoction on doxorubicin-induced cognitive impairment in breast cancer animal model. [PDF]

Front Oncol
Wang X, Sun Q, Li J, Lai B, Pei X, Chen N.   +5 more
europepmc   +1 more source

The Effects of Neuronal <i>Fyn</i> Knockdown in the Hippocampus in the Rat Kainate Model of Temporal Lobe Epilepsy. [PDF]

Cells
Rao NS, Putra M, Meyer C, Parameswaran S, Thippeswamy T.   +4 more
europepmc   +1 more source

Auricular Transcutaneous Vagus Nerve Stimulation Enhances Post-Stroke Neurological and Cognitive Recovery in Mice by Suppressing Ferroptosis Through α7 Nicotinic Acetylcholine Receptor Activation. [PDF]

CNS Neurosci Ther
Gong H, Zheng F, Niu B, Wang B, Xu L, Yang Y, Wang J, Tang X, Bi Y.   +8 more
europepmc   +1 more source