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Hirschsprung?s disease as a neurochristopathy
Pediatric Surgery International, 1996Recent molecular-genetic and histochemical studies of intestinal aganglionosis have confirmed the initial classification established by Bolande, who considered Hirschsprung's disease (HD) a neurocristopathy. This paper is a critical review of the results of molecular-genetic studies carried out from 1992 to date.
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Reoperation for Hirschsprung's disease
Journal of Pediatric Surgery, 1999Reoperation for Hirschsprung's disease traditionally has been used for patients with anastomotic leaks or stricture or with severe constipation from retained aganglionic segment or neuronal dysplasia, but there is little information regarding its use for other complications and the long-term outcome in these patients.In a 23-year period, 107 infants ...
T R, Weber +3 more
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Variant Hirschsprung's disease
Journal of Pediatric Surgery, 1997There are many clinical conditions that resemble Hirschsprung's disease despite the presence of ganglia cells on rectal biopsy. This group has focused its research interest into delineating variant Hirschsprung's disease based on specific histochemical, immunohistochemical, silver staining and electron microscopic studies.
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Hirschsprung's Disease in Infants
Archives of Surgery, 1959Introduction Until recently, the clinical course of aganglionic megacolon was considered to be of a chronic and protracted nature with obstipation as the presenting symptom. In the past few years, however, several excellent papers have appeared by Dorman 1 and Sieber and Girdany 2 in which the severe and fulminating course of symptomatic Hirschsprung ...
T C, JEWETT, L J, LEAHY, J, LANIGAN
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Hirschsprung's disease?a review
International Journal of Colorectal Disease, 1991Hirschsprung's disease is not the easiest of diseases to diagnose and there is a range of similar diseases which merge into the problem. The lack of knowledge as to its aetiology means that prevention is not possible. The wide range of treatments suggests that none of them give ideal results every time, although they each have their adherents.
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The Surgery of Hirschsprung’s Disease
Surgical Clinics of North America, 1983The author concisely describes what Hirschsprung’s disease is, how it can be diagnosed, and what advantages accrue to the various “definitive” treatments proposed by surgeons.
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Hirschsprung’s disease and the brain
Pediatric Surgery International, 2010A link between factors governing brain development and the development of the ENS is not surprising as both processes are largely controlled by the same or similar neural growth factors which are expressed at more or less in the same spatio-temporal time frame.
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