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Seminars in Pediatric Surgery, 2022
Hirschsprung disease (HD) is a complex surgical and medical problem that appears to have varied health and social outcomes with the age and neurodevelopmental state of patients. In general, long-term outcomes are thought to be good for the majority of patients despite recognized problems with constipation and/or fecal incontinence.
Scott S, Short +2 more
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Hirschsprung disease (HD) is a complex surgical and medical problem that appears to have varied health and social outcomes with the age and neurodevelopmental state of patients. In general, long-term outcomes are thought to be good for the majority of patients despite recognized problems with constipation and/or fecal incontinence.
Scott S, Short +2 more
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Pediatrics In Review, 1995
In 1886, Harald Hirschsprung first described a disorder in newborns of severe constipation with dilatation and hypertrophy of the colon. No mechanical obstruction could be demonstrated, but there appeared to be an area of spasm that prevented the movement of lumen contents through the sigmoid or rectum. This disorder, termed Hirschsprung disease, later
C, Rudolph, L, Benaroch
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In 1886, Harald Hirschsprung first described a disorder in newborns of severe constipation with dilatation and hypertrophy of the colon. No mechanical obstruction could be demonstrated, but there appeared to be an area of spasm that prevented the movement of lumen contents through the sigmoid or rectum. This disorder, termed Hirschsprung disease, later
C, Rudolph, L, Benaroch
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Current Treatment Options in Gastroenterology, 2003
Hirschsprung's disease (HSCR) is the most common congenital malformation of the enteric nervous system and requires early diagnosis and surgical repair for the best comprehensive outcome. The early diagnosis of this disorder permits the use of primary endorectal pull-through (PERPT), which is now the definitive surgical therapy for HSCR.
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Hirschsprung's disease (HSCR) is the most common congenital malformation of the enteric nervous system and requires early diagnosis and surgical repair for the best comprehensive outcome. The early diagnosis of this disorder permits the use of primary endorectal pull-through (PERPT), which is now the definitive surgical therapy for HSCR.
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Journal of Pediatric Surgery, 1989
This report presents a series of 17 patients with adult Hirschsprung's disease treated at the National Taiwan University Hospital and its affiliated hospitals from 1965 to 1988. Adults with Hirschsprung's disease may present with symptoms and operative findings different from those of children with Hirschsprung's disease.
W T, Hung +6 more
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This report presents a series of 17 patients with adult Hirschsprung's disease treated at the National Taiwan University Hospital and its affiliated hospitals from 1965 to 1988. Adults with Hirschsprung's disease may present with symptoms and operative findings different from those of children with Hirschsprung's disease.
W T, Hung +6 more
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Surgical Clinics of North America, 1976
Hirschsprung's disease or aganglionic megacolon is an anomaly caused by the absence of ganglion cells in the myenteric plexus of the distal colon. It produces intestinal obstruction or lethal enterocolitis in the neonatal period and constipation of varying degree in the older child.
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Hirschsprung's disease or aganglionic megacolon is an anomaly caused by the absence of ganglion cells in the myenteric plexus of the distal colon. It produces intestinal obstruction or lethal enterocolitis in the neonatal period and constipation of varying degree in the older child.
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Clinical Radiology, 1991
Two cases of adult Hirschsprung's disease are reported along with a review of 47 cases reported in the literature. Chronic constipation is present in almost all cases. The barium enema examination may suggest the diagnosis if an area of smooth narrowing with proximal dilatation is seen (83%), but biopsy proof of absence of ganglion cells is necessary ...
N L, Crocker, J M, Messmer
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Two cases of adult Hirschsprung's disease are reported along with a review of 47 cases reported in the literature. Chronic constipation is present in almost all cases. The barium enema examination may suggest the diagnosis if an area of smooth narrowing with proximal dilatation is seen (83%), but biopsy proof of absence of ganglion cells is necessary ...
N L, Crocker, J M, Messmer
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Variant Hirschsprung’s disease
Seminars in Pediatric Surgery, 2004Conditions that clinically resemble HD despite the presence of ganglion cells on suction rectal biopsy results, can be diagnosed by providing an adequate biopsy and employing a variety of histological techniques. Intestinal neuronal dysplasia is a distinct clinical entity that can be clearly proven histologically.
Prem, Puri, Udo, Rolle
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Genetics of Hirschsprung’s disease
Pediatric surgery international (Print), 2023C. Tang +4 more
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Neonatal Hirschsprung’s disease
The Indian Journal of Pediatrics, 2000Since the classic description of this disease by Harold Hirschsprung's. In 1886 just over a century ago, there has been a marked evolution in the diagnostic modalities, understanding of the pathophysiology, unraveling of genetic association and the treatment approach of this disease.
A, Lall, D K, Gupta, M, Bajpai
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Adult Segmental Hirschsprung Disease
Southern Medical Journal, 2009Hirschsprung disease (HD) is characterized by aganglionosis, which mainly occurs in the rectum and distal sigmoid colon. Typical HD is seldom diagnosed in adulthood, and segmental involvement is very rare. A 37-year-old man suffered from refractory constipation for 20 years.
Başar, Ömer +4 more
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