Results 41 to 50 of about 4,311 (162)

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

Third Space Endoscopic Therapies for Benign Motility Disorders: A Narrative Review

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives To review the evidence base, evolution, outcomes, adverse events (AEs), and management for third‐space endoscopy (TSE) procedures for management of benign motility disorders. Methods This review examines TSE procedures for motility disorders, reviewing the current available techniques, success, outcomes, and long‐term outcomes from ...
Sanjana Bhagwat, Amol Bapaye
wiley   +1 more source

Recurrent Congenital Hiatal Hernia After Laparoscopic Repair Complicated by Gastric Perforation and Abdominal Compartment Syndrome

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Complete excision of the hernial sac during congenital hiatal hernia repair may help prevent recurrence. This case also emphasizes the importance of early recognition and prompt management of abdominal compartment syndrome when progressive abdominal distension and organ dysfunction develop postoperatively.
Takayuki Fujii, Yui Noguchi, Nanami Harada, Hiroto Katami, Aya Tanaka   +4 more
wiley   +1 more source

Variants of Hirschsprung disease

Seminars in Pediatric Surgery, 2012
Variants of Hirschsprung disease are conditions that clinically resemble Hirschsprung disease, despite the presence of ganglion cells in rectal suction biopsies. The characterization and differentiation of various entities are mainly based on histologic, immunohistochemical, and electron microscopy findings of biopsies from patients with functional ...
Prem, Puri, Jan-Hendrik, Gosemann
openaire   +2 more sources

Outcome of Primary Transanal pull through for Short segment Hirschsprung's disease in children without frozen section

Journal of Pediatric Surgery Open, 2023
Background: Hirschsprung's disease is a congenital disorder of the enteric nervous system. There are many type of pull through surgeries (e.g.) Duhamel, Soave, Swenson etc. and are done openly as well as laparoscopically.
Farooq Abdullah, Khawar Saeed, Ubaid Ullah Khan, Abdul Hameed, Syed Salah ud Din Shah   +4 more
doaj   +1 more source

Sigmoid Volvulus in a Young Adult With Cerebral Palsy: A Case Managed by the Paul‐Mikulicz Procedure

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 25‐year‐old male with cerebral palsy presented with sigmoid volvulus complicated by ischemia and fecal impaction—an underrecognized but serious risk in this population. Emergency Paul‐Mikulicz colostomy achieved safe resection. Clinicians should suspect volvulus early in CP patients, and proactive bowel management is essential.
Mehwish Saleem, Asad Ahsan, Shahroze Wajid, Muhammad Muaz, Bahzad Akram Khan, Arham Saif, Muhammad Husnain Ahmad   +6 more
wiley   +1 more source

Anorectal manometry under adequate sedation or anesthesia as a highly reliable diagnostic tool for Hirschsprung's disease in neonates and young infants: A multicenter retrospective study

Global Pediatrics
Background: Hirschsprung's disease is a congenital disorder characterized by the absence of enteric ganglion cells. The diagnostic gold standard for Hirschsprung's disease is a rectal mucosal biopsy; however, its accuracy in neonates and young infants ...
Yohei Sanmoto, Atsuki Naoe, Yudai Goto, Mikihiro Inoue, Kouji Masumoto   +4 more
doaj   +1 more source

Parenteral nutrition and hospital outcomes in Australian adults: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, Volume 50, Issue 7, Page 1003-1013, October 2026.
Abstract Background There is limited information regarding real‐world use of parenteral nutrition in hospitals. The objective of the study was to provide a real‐world description of parenteral nutrition administration in hospitalized patients. Methods This was a descriptive cohort study in 507 hospitalized adults who received parenteral nutrition at ...
Frank M. P. van Haren, Sumeet Rai, Andrew Thomson, Josie Russell‐Brown, Mary Nourse, Shakira Spiller, Louise Herlihy, Sean Weng Chan, Peter Velloza, Matthew H. Anstey, Robert N. Palmer, Bianca Mammana, Tania Elderkin, Adam Visser, Matt Brain, Sarah Mineall, Emma J. Ridley   +16 more
wiley   +1 more source

Retrospective study of Hirschsprung's disease in Erbil city/Iraq during 2004–2016

Medical Journal of Babylon, 2020
Background: Hirschsprung's disease is caused by the failure of ganglion cells to migrate cephalocaudal through the neural crest during 4–12 weeks of gestation, causing an absence of ganglion cells in all or part of the colon.
Suhel Mawlud Alnajjar, Jawhar Tahir Omer, Salah Abubakir Ali   +2 more
doaj   +1 more source

Effectiveness of various surgical methods in treatment of Hirschsprung’s disease in children [PDF]

Vojnosanitetski Pregled, 2016
Background/Aim. Hirschsprung’s disease is the most common identifiable developmental disorder of the enteric nervous system, characterized by a failure of its formation in a variable segment of distal bowel.
Lukač Marija, Sinđić-Antunović Sanja, Vujović Dragana, Petronić Ivana, Nikolić Dejan, Radlović Vladimir, Krstajić Tamara, Krstić Zoran   +7 more
doaj   +1 more source